Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yfcHSimilar to E. coli putative sugar nucleotide epimerase (AAC75364.1); Blastp hit to AAC75364.1 (297 aa), 86% identity in aa 1 - 297. (297 aa)    
Predicted Functional Partners:
blc
Outer membrane lipoprotein; Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.
    0.924
lepB
Leader peptidase (signal peptidase I), serine protease; Signal peptidase I. (SW:LEP_SALTY); Belongs to the peptidase S26 family.
   
    0.823
minE
Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
   
  
 0.817
yfiA
Ribosome associated factor; Stabilizes ribosomes against dissociation; similar to E. coli putative yhbH sigma 54 modulator (AAC75646.1); Blastp hit to AAC75646.1 (113 aa), 91% identity in aa 1 - 112.
   
    0.674
rne
RNase E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.
   
    0.636
ybjT
Putative nucleoside-diphosphate-sugar epimerase; Similar to E. coli putative dTDP-glucose enzyme (AAC73956.1); Blastp hit to AAC73956.1 (486 aa), 84% identity in aa 11 - 486.
 
    0.633
cspC
Cold shock protein; Multicopy suppresses mukB mutants, putative regulator; cold shock-like protein CSPC. (SW:CSPC_SALTY).
   
    0.610
yfcG
Similar to E. coli putative S-transferase (AAC75362.1); Blastp hit to AAC75362.1 (215 aa), 83% identity in aa 1 - 208.
  
    0.604
ygiE
Putative divalent heavy-metal cations transporter; Mediates zinc uptake. May also transport other divalent cations such as copper and cadmium ions (By similarity); Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
  
    0.603
rmf
Ribosome modulation factor (involved in dimerization of 70S ribosomes); During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes). May form immature 90S particles, which are converted to mature 100S ribosomes by the hibernation promoting factor Hpf.
   
    0.585
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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