close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfcHSimilar to E. coli putative sugar nucleotide epimerase (AAC75364.1); Blastp hit to AAC75364.1 (297 aa), 86% identity in aa 1 - 297. (297 aa)    
Predicted Functional Partners:
yfcC
Putative integral membrane protein; Similar to E. coli putative S-transferase (AAC75358.1); Blastp hit to AAC75358.1 (513 aa), 91% identity in aa 8 - 513.
      
 0.952
blc
Outer membrane lipoprotein; Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.
    0.924
lepB
Leader peptidase (signal peptidase I), serine protease; Signal peptidase I. (SW:LEP_SALTY); Belongs to the peptidase S26 family.
   
    0.777
ybjT
Putative nucleoside-diphosphate-sugar epimerase; Similar to E. coli putative dTDP-glucose enzyme (AAC73956.1); Blastp hit to AAC73956.1 (486 aa), 84% identity in aa 11 - 486.
 
    0.705
minE
Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
   
  
 0.667
arcA-2
Putative arginine deiminase.
   
    0.566
yfcG
Similar to E. coli putative S-transferase (AAC75362.1); Blastp hit to AAC75362.1 (215 aa), 83% identity in aa 1 - 208.
  
    0.563
yihT
Putative aldolase; Cleaves 6-deoxy-6-sulfo-D-fructose 1-phosphate (SFP) to form dihydroxyacetone phosphate (DHAP) and 3-sulfolactaldehyde (SLA). Belongs to the aldolase LacD family.
   
    0.563
ygiE
Putative divalent heavy-metal cations transporter; Mediates zinc uptake. May also transport other divalent cations such as copper and cadmium ions (By similarity); Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
  
    0.546
lolB
Outer membrane lipoprotein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
  
    0.539
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.