STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hisJHistidine transport protein; Part of the histidine permease ABC transporter. Binds histidine. Interacts with HisQMP and stimulates ATPase activity of HisP, which results in histidine translocation. May have some additional function(s) in translocation that is independent of the stimulation of ATP hydrolysis. (260 aa)    
Predicted Functional Partners:
hisP
Histidine and lysine/arginine/ornithine transport protein; Part of the histidine permease ABC transporter. Also part of a lysine/arginine/ornithine transporter. Responsible for energy coupling to the transport system.
 
 0.999
hisM
Histidine and lysine/arginine/ornithine transport protein; Part of the histidine permease ABC transporter. Also part of a lysine/arginine/ornithine transporter. Probably responsible for the translocation of the substrate across the membrane. Required to relay the ATPase-inducing signal from the solute-binding protein to HisP.
 
 0.999
hisQ
Histidine and lysine/arginine/ornithine transport system; Part of the histidine permease ABC transporter. Also part of a lysine/arginine/ornithine transporter. Probably responsible for the translocation of the substrate across the membrane. Required to relay the ATPase-inducing signal from the solute-binding protein to HisP.
 0.999
glnP
ABC superfamily (membrane); similar to E. coli glutamine high-affinity transport system; membrane component (AAC73897.1); Blastp hit to AAC73897.1 (219 aa), 96% identity in aa 1 - 219.
 
 0.981
artM
Arginine 3rd transport system; ABC superfamily (membrane); similar to E. coli arginine 3rd transport system permease protein (AAC73948.1); Blastp hit to AAC73948.1 (222 aa), 94% identity in aa 1 - 222.
  
 0.981
yecS
Putative ABC-type amino acid transporter; Permease component; similar to E. coli putative transport system permease protein (former yecC) (AAC74985.1); Blastp hit to AAC74985.1 (222 aa), 93% identity in aa 1 - 222.
 
 0.981
gltK
Glutamate/aspartate transporter; ABC superfamily (membrane); similar to E. coli glutamate/aspartate transport system permease (AAC73754.1); Blastp hit to AAC73754.1 (224 aa), 95% identity in aa 1 - 223.
 
 0.971
artQ
Arginine 3rd transport system; ABC superfamily (membrane); similar to E. coli arginine 3rd transport system permease protein (AAC73949.1); Blastp hit to AAC73949.1 (238 aa), 94% identity in aa 1 - 237.
 
 0.968
artP
Arginine transport system; ABC superfamily (atp&memb); similar to E. coli ATP-binding component of 3rd arginine transport system (AAC73951.1); Blastp hit to AAC73951.1 (242 aa), 95% identity in aa 1 - 242.
  
 0.916
STM1636
Similar to E. coli putative transport system permease protein (former yecC) (AAC74985.1); Blastp hit to AAC74985.1 (222 aa), 34% identity in aa 10 - 216.
 
 0.874
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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