Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
STM2361Putative regulatory protein; Similar to E. coli response regulator of ato, ornithine decarboxylase antizyme (sensor ATOS) (AAC75280.1); Blastp hit to AAC75280.1 (461 aa), 39% identity in aa 122 - 456. (475 aa)    
Predicted Functional Partners:
dsdC
LysR family transcriptional activator; Similar to E. coli D-serine dehydratase (deaminase) transcriptional activator (AAC75423.1); Blastp hit to AAC75423.1 (311 aa), 90% identity in aa 1 - 307; Belongs to the LysR transcriptional regulatory family.
   
  
 0.953
STM2360
Similar to E. coli diaminopimelate decarboxylase (AAC75877.1); Blastp hit to AAC75877.1 (420 aa), 27% identity in aa 182 - 419, 26% identity in aa 20 - 289.
  
  
 0.945
rpoN
Sigma N factor of RNA polymerase; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of enzymes involved in arginine catabolism. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for the receipt of the melting signal from the remotely bound activator protein GlnG(NtrC).
 
   
 0.799
fbaB
3-oxoacyl-[acyl-carrier-protein] synthase I; Similar to E. coli orf, hypothetical protein (AAC75158.1); Blastp hit to AAC75158.1 (374 aa), 96% identity in aa 25 - 374.
    
   0.575
STM0571
Putative inner membrane protein; Unknown (gi|2896134).
  
  
0.560
STM2358
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76406.1); Blastp hit to AAC76406.1 (387 aa), 27% identity in aa 33 - 293.
 
     0.482
STM0652
Putative sigma-54 dependent transcriptional regulator; Similar to E. coli response regulator of ato, ornithine decarboxylase antizyme (sensor ATOS) (AAC75280.1); Blastp hit to AAC75280.1 (461 aa), 37% identity in aa 67 - 453.
  
  
0.476
STM2359
Similar to E. coli acid sensitivity protein, putative transporter (AAC74565.1); Blastp hit to AAC74565.1 (511 aa), 25% identity in aa 15 - 479.
 
    0.474
rtcR
Sigma N (sigma 54)-dependent regulator of rtcBA expression; EBP family; similar to E. coli putative 2-component regulator (AAC76447.1); Blastp hit to AAC76447.1 (532 aa), 84% identity in aa 1 - 527.
  
  
0.463
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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