STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STM2374Putatiave helix-turn-helix regulatory protein; Similar to E. coli regulatory factor of maltose metabolism; similar to Ner repressor protein of phage Mu (AAC76220.1); Blastp hit to AAC76220.1 (92 aa), 50% identity in aa 1 - 73. (82 aa)    
Predicted Functional Partners:
pagP
PhoPQ-activated gene; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors. Required for resistance to cationic antimicrobial peptides (CAMPs). Modifications of lipid A with a palmitate chain allow to evade host immune defenses by resisting antimicrobial peptides and attenuating the inflammatory response to infection triggered by lipopolysaccharide through the Toll-like receptor 4 (TLR4) signal transduction pathway.
  
     0.537
STM2373
Putative cytoplasmic protein.
  
    0.533
STM2375
Putative cytoplasmic protein.
  
    0.473
STM2376
Putative periplasmic protein.
  
    0.471
yhbP
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76188.1); Blastp hit to AAC76188.1 (147 aa), 83% identity in aa 1 - 147; Belongs to the UPF0306 family.
  
     0.467
emrR
Transcriptional repressor of emrAB operon; MarR family; similar to E. coli regulator of plasmid mcrB operon (microcin B17 synthesis) (AAC75731.1); Blastp hit to AAC75731.1 (176 aa), 93% identity in aa 1 - 175.
  
     0.442
ynbE
Putative outer membrane lipoprotein; Similar to E. coli orf, hypothetical protein (AAC74464.1); Blastp hit to AAC74464.1 (61 aa), 73% identity in aa 1 - 61.
  
    0.426
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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