| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aroC | mepA | STM2384 | STM2383 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Penicillin-insensitive murein DD-endopeptidase; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus. Belongs to the peptidase M74 family. | 0.912 |
| aroC | yfcA | STM2384 | STM2382 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Similar to E. coli putative structural protein (AAC75387.1); Blastp hit to AAC75387.1 (269 aa), 90% identity in aa 1 - 269. | 0.825 |
| aroC | yfcB | STM2384 | STM2385 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Putative methylase; Specifically methylates the 50S ribosomal protein L3 on 'Gln- 150'; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily. | 0.933 |
| aroC | yfcL | STM2384 | STM2380 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75385.1); Blastp hit to AAC75385.1 (92 aa), 85% identity in aa 1 - 91. | 0.780 |
| aroC | yfcM | STM2384 | STM2381 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Putative cytoplasmic protein; Similar to E. coli putative transporting ATPase (AAC75386.1); Blastp hit to AAC75386.1 (182 aa), 92% identity in aa 1 - 182. | 0.824 |
| cysI | cysJ | STM2947 | STM2948 | NADPH dependent sulfite reductase, alpha subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Sulfite reductase, beta (flavoprotein) subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | 0.999 |
| cysI | yfcA | STM2947 | STM2382 | NADPH dependent sulfite reductase, alpha subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Similar to E. coli putative structural protein (AAC75387.1); Blastp hit to AAC75387.1 (269 aa), 90% identity in aa 1 - 269. | 0.729 |
| cysJ | cysI | STM2948 | STM2947 | Sulfite reductase, beta (flavoprotein) subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | NADPH dependent sulfite reductase, alpha subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.999 |
| cysJ | yfcA | STM2948 | STM2382 | Sulfite reductase, beta (flavoprotein) subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Similar to E. coli putative structural protein (AAC75387.1); Blastp hit to AAC75387.1 (269 aa), 90% identity in aa 1 - 269. | 0.701 |
| mepA | aroC | STM2383 | STM2384 | Penicillin-insensitive murein DD-endopeptidase; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus. Belongs to the peptidase M74 family. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.912 |
| mepA | yfcA | STM2383 | STM2382 | Penicillin-insensitive murein DD-endopeptidase; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus. Belongs to the peptidase M74 family. | Similar to E. coli putative structural protein (AAC75387.1); Blastp hit to AAC75387.1 (269 aa), 90% identity in aa 1 - 269. | 0.957 |
| mepA | yfcB | STM2383 | STM2385 | Penicillin-insensitive murein DD-endopeptidase; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus. Belongs to the peptidase M74 family. | Putative methylase; Specifically methylates the 50S ribosomal protein L3 on 'Gln- 150'; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily. | 0.922 |
| mepA | yfcL | STM2383 | STM2380 | Penicillin-insensitive murein DD-endopeptidase; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus. Belongs to the peptidase M74 family. | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75385.1); Blastp hit to AAC75385.1 (92 aa), 85% identity in aa 1 - 91. | 0.780 |
| mepA | yfcM | STM2383 | STM2381 | Penicillin-insensitive murein DD-endopeptidase; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus. Belongs to the peptidase M74 family. | Putative cytoplasmic protein; Similar to E. coli putative transporting ATPase (AAC75386.1); Blastp hit to AAC75386.1 (182 aa), 92% identity in aa 1 - 182. | 0.839 |
| serC | yfcA | STM0977 | STM2382 | 3-phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | Similar to E. coli putative structural protein (AAC75387.1); Blastp hit to AAC75387.1 (269 aa), 90% identity in aa 1 - 269. | 0.617 |
| yacC | ydjA | STM0167 | STM1296 | Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73233.1); Blastp hit to AAC73233.1 (156 aa), 95% identity in aa 42 - 156. | Putative oxidoreductase; Similar to E. coli orf, hypothetical protein (AAC74835.1); Blastp hit to AAC74835.1 (183 aa), 88% identity in aa 1 - 183. | 0.676 |
| yacC | yfcA | STM0167 | STM2382 | Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73233.1); Blastp hit to AAC73233.1 (156 aa), 95% identity in aa 42 - 156. | Similar to E. coli putative structural protein (AAC75387.1); Blastp hit to AAC75387.1 (269 aa), 90% identity in aa 1 - 269. | 0.721 |
| ydjA | yacC | STM1296 | STM0167 | Putative oxidoreductase; Similar to E. coli orf, hypothetical protein (AAC74835.1); Blastp hit to AAC74835.1 (183 aa), 88% identity in aa 1 - 183. | Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73233.1); Blastp hit to AAC73233.1 (156 aa), 95% identity in aa 42 - 156. | 0.676 |
| ydjA | yfcA | STM1296 | STM2382 | Putative oxidoreductase; Similar to E. coli orf, hypothetical protein (AAC74835.1); Blastp hit to AAC74835.1 (183 aa), 88% identity in aa 1 - 183. | Similar to E. coli putative structural protein (AAC75387.1); Blastp hit to AAC75387.1 (269 aa), 90% identity in aa 1 - 269. | 0.924 |
| yfcA | aroC | STM2382 | STM2384 | Similar to E. coli putative structural protein (AAC75387.1); Blastp hit to AAC75387.1 (269 aa), 90% identity in aa 1 - 269. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.825 |
