STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mepAPenicillin-insensitive murein DD-endopeptidase; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus. Belongs to the peptidase M74 family. (274 aa)    
Predicted Functional Partners:
yfcA
Similar to E. coli putative structural protein (AAC75387.1); Blastp hit to AAC75387.1 (269 aa), 90% identity in aa 1 - 269.
 
    0.957
yfcB
Putative methylase; Specifically methylates the 50S ribosomal protein L3 on 'Gln- 150'; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
 
  
 0.922
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.912
ydhE
Putative MATE family transport protein; Multidrug efflux pump that functions probably as a Na(+)/drug antiporter; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
      
 0.871
dinF
DNA-damage-inducible protein F; Induced by UV and mitomycin C; SOS, lexA regulon; similar to E. coli DNA-damage-inducible protein F (AAC77014.1); Blastp hit to AAC77014.1 (459 aa), 89% identity in aa 19 - 457.
      
 0.853
yfcM
Putative cytoplasmic protein; Similar to E. coli putative transporting ATPase (AAC75386.1); Blastp hit to AAC75386.1 (182 aa), 92% identity in aa 1 - 182.
  
    0.839
yfcL
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75385.1); Blastp hit to AAC75385.1 (92 aa), 85% identity in aa 1 - 91.
  
    0.780
ybjL
Similar to E. coli putative transport protein (AAC73934.1); Blastp hit to AAC73934.1 (561 aa), 96% identity in aa 1 - 561.
  
   
 0.756
ycbK
Putative outer membrane protein; Similar to E. coli orf, hypothetical protein (AAC74012.1); Blastp hit to AAC74012.1 (182 aa), 95% identity in aa 1 - 182.
  
     0.735
yedA
Similar to E. coli putative transmembrane subunit (AAC75025.1); Blastp hit to AAC75025.1 (306 aa), 89% identity in aa 1 - 298.
   
  
 0.728
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.