Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yfcBPutative methylase; Specifically methylates the 50S ribosomal protein L3 on 'Gln- 150'; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily. (310 aa)    
Predicted Functional Partners:
prmA
Methylation of 50S ribosomal subunit protein L11; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.
      
 0.940
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.933
mepA
Penicillin-insensitive murein DD-endopeptidase; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus. Belongs to the peptidase M74 family.
 
  
 0.922
prfA
Peptide chain release factor RF-1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
 
 0.870
yfcA
Similar to E. coli putative structural protein (AAC75387.1); Blastp hit to AAC75387.1 (269 aa), 90% identity in aa 1 - 269.
  
    0.771
yfcM
Putative cytoplasmic protein; Similar to E. coli putative transporting ATPase (AAC75386.1); Blastp hit to AAC75386.1 (182 aa), 92% identity in aa 1 - 182.
  
    0.766
yjhP
Similar to E. coli putative methyltransferase (AAC77262.1); Blastp hit to AAC77262.1 (248 aa), 30% identity in aa 1 - 138.
     
 0.760
yafS
Putative SAM-dependent methyltransferase; Similar to E. coli orf, hypothetical protein (AAC73318.1); Blastp hit to AAC73318.1 (246 aa), 86% identity in aa 7 - 244.
 
   
 0.733
yafE
Putative methyltransferase in menaquinone/biotin biosynthesis; Similar to E. coli putative biotin synthesis protein (AAC73315.1); Blastp hit to AAC73315.1 (207 aa), 71% identity in aa 3 - 206.
     
 0.726
yfcL
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75385.1); Blastp hit to AAC75385.1 (92 aa), 85% identity in aa 1 - 91.
       0.705
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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