Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yfcNPutative Smr domain containing protein; Similar to E. coli orf, hypothetical protein (AAC75391.1); Blastp hit to AAC75391.1 (183 aa), 93% identity in aa 1 - 183; Belongs to the UPF0115 family. (183 aa)    
Predicted Functional Partners:
sixA
Phosphohistidine phosphatase; Similar to E. coli orf, hypothetical protein (AAC75400.1); Blastp hit to AAC75400.1 (161 aa), 89% identity in aa 1 - 161.
  
   
 0.925
rplY
50S ribosomal subunit protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family.
  
 
   0.720
rplD
50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). Forms part of the polypeptide exit tunnel. Belongs to the universal ribosomal protein uL4 family.
  
 
   0.708
rpsJ
30S ribosomal subunit protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
 
 0.694
rpsU
30S ribosomal protein S21. (SW:RS21_ECOLI); Belongs to the bacterial ribosomal protein bS21 family.
  
 
   0.690
ydaL
Putative Smr domain protein; Similar to E. coli orf, hypothetical protein (AAC74422.1); Blastp hit to AAC74422.1 (187 aa), 86% identity in aa 1 - 187.
  
   
 0.682
rpsG
30S ribosomal subunit protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
   0.644
rpsL
30S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy.
   
   0.644
rpsT
30S ribosomal subunit protein S20; Binds directly to 16S ribosomal RNA.
   
   0.636
rpsB
Similar to E. coli 30S ribosomal subunit protein S2 (AAC73280.1); Blastp hit to AAC73280.1 (241 aa), 97% identity in aa 1 - 241; Belongs to the universal ribosomal protein uS2 family.
    
   0.635
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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