STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vacJSimilar to E. coli lipoprotein precursor (AAC75406.1); Blastp hit to AAC75406.1 (251 aa), 94% identity in aa 1 - 251. (251 aa)    
Predicted Functional Partners:
yrbC
Putative ABC superfamily transport protein; Atp&memb; similar to E. coli orf, hypothetical protein (AAC76224.1); Blastp hit to AAC76224.1 (211 aa), 93% identity in aa 1 - 211.
 
 
 
 0.970
yrbE
Putative ABC superfamily transport protein; Membr; similar to E. coli orf, hypothetical protein (AAC76226.1); Blastp hit to AAC76226.1 (260 aa), 96% identity in aa 1 - 260.
 
   
 0.927
yrbD
Putative ABC superfamily transport protein; Bind_prot; similar to E. coli orf, hypothetical protein (AAC76225.1); Blastp hit to AAC76225.1 (183 aa), 87% identity in aa 1 - 183.
 
  
 0.917
imp
Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
 
  
 0.886
ompC
Outer membrane protein 1b (ib;c); Forms pores that allow passive diffusion of small molecules across the outer membrane.
   
 
 0.844
yrbB
Putative STAS domain protein; Similar to E. coli orf, hypothetical protein (AAC76223.1); Blastp hit to AAC76223.1 (129 aa), 69% identity in aa 33 - 129.
     
 0.838
yrbF
Putative ABC superfamily transport protein; Atp_bind; similar to E. coli putative ATP-binding component of a transport system (AAC76227.1); Blastp hit to AAC76227.1 (269 aa), 94% identity in aa 1 - 266.
 
  
 0.810
lpxC
UDP-3-O-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
   
  
 0.797
lpxA
UDP-N-acetylglucosamine acetyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
   
  
 0.770
ompA
Putative membrane component hydrogenase; With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.
  
  
 0.752
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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