Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yfdCSimilar to E. coli putative transport (AAC75407.1); Blastp hit to AAC75407.1 (310 aa), 87% identity in aa 1 - 304. (313 aa)    
Predicted Functional Partners:
nirC
FNT family nitrite transport protein; Catalyzes nitrite uptake and nitrite export across the cytoplasmic membrane; Belongs to the FNT transporter (TC 2.A.44) family.
      
 0.856
focA
Formate channel 1; putative FNT family member; similar to E. coli probable formate transporter (formate channel 1) (AAC73990.1); Blastp hit to AAC73990.1 (285 aa), 95% identity in aa 1 - 285.
      
 0.852
pgtE
Outer membrane protein E; Protease that can cleave T7 RNA polymerase. Specific for paired basic residues; Belongs to the peptidase A26 family.
   
  
 0.733
yihV
Putative sugar kinase; Phosphorylates 6-deoxy-6-sulfo-D-fructose (SF) to 6-deoxy-6- sulfo-D-fructose 1-phosphate (SFP); Belongs to the carbohydrate kinase PfkB family.
      
 0.719
purC
SAICAR synthetase; similar to E. coli phosphoribosylaminoimidazole-succinocarboxamide synthetase = SAICAR synthetase (AAC75529.1); Blastp hit to AAC75529.1 (237 aa), 94% identity in aa 1 - 237.
      
 0.675
yqaE
Putative YqaE family transport protein; Similar to E. coli orf, hypothetical protein (AAC75713.1); Blastp hit to AAC75713.1 (52 aa), 94% identity in aa 1 - 51.
  
     0.591
yadF
Putative carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
  
    0.590
nrfE
Formate-dependent nitrite reductase; Possible subunit of a heme lyase.
      
 0.512
nifJ
Similar to E. coli putative oxidoreductase, Fe-S subunit (AAC74460.1); Blastp hit to AAC74460.1 (1174 aa), 92% identity in aa 1 - 1174.
     
 0.497
yegS
Putative diacylglycerol kinase catalytic domain containing protein; In vitro does not phosphorylate diacylglycerol, sphingosine, N,N-dimethylsphingosine; threo-dihydrosphingosine, erythro- dihydrosphingosine, C2 ceramide, C6 ceramide, phosphatidylinositol or dimethylsphingosine. The potential in vivo substrate is unknown.
  
  
 0.465
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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