Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ypeCPutative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75449.1); Blastp hit to AAC75449.1 (108 aa), 91% identity in aa 1 - 108. (108 aa)    
Predicted Functional Partners:
STM1863
Putative inner membrane protein.
      
 0.895
ygaC
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75718.1); Blastp hit to AAC75718.1 (114 aa), 88% identity in aa 1 - 112.
   
  
 0.860
yfeO
Putative chloride channel permease; Similar to E. coli orf, hypothetical protein (AAC75448.1); Blastp hit to AAC75448.1 (418 aa), 80% identity in aa 1 - 408.
      
 0.770
acrZ
Putative outer membrane or exported; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.
      
 0.768
slrB
Similar to E. coli PTS system, glucitol/sorbitol-specific enzyme IIA component (AAC75746.1); Blastp hit to AAC75746.1 (123 aa), 82% identity in aa 1 - 118.
      
 0.766
yjcB
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC77030.1); Blastp hit to AAC77030.1 (116 aa), 83% identity in aa 24 - 116.
      
 0.754
yhcC
Putative FeS oxidoreductase; Similar to E. coli orf, hypothetical protein (AAC76243.1); Blastp hit to AAC76243.1 (309 aa), 94% identity in aa 1 - 307.
      
 0.741
glnP
ABC superfamily (membrane); similar to E. coli glutamine high-affinity transport system; membrane component (AAC73897.1); Blastp hit to AAC73897.1 (219 aa), 96% identity in aa 1 - 219.
      
 0.676
srlE
One of two IIC components; similar to E. coli PTS system, glucitol/sorbitol-specific IIB component and second of two IIC components (AAC75745.1); Blastp hit to AAC75745.1 (319 aa), 92% identity in aa 1 - 319.
      
 0.673
ybaO
Similar to E. coli putative LRP-like transcriptional regulator (AAC73550.1); Blastp hit to AAC73550.1 (181 aa), 95% identity in aa 30 - 181.
      
 0.672
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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