Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yfeDPutative negative regulator; Similar to E. coli orf, hypothetical protein (AAC75456.1); Blastp hit to AAC75456.1 (130 aa), 70% identity in aa 1 - 129. (130 aa)    
Predicted Functional Partners:
yfeC
Putative negative regulator; Similar to E. coli orf, hypothetical protein (AAC75455.1); Blastp hit to AAC75455.1 (119 aa), 79% identity in aa 1 - 119.
  
  
0.862
smg
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76309.1); Blastp hit to AAC76309.1 (157 aa), 94% identity in aa 1 - 157; Belongs to the Smg family.
      
 0.740
yfiE
Similar to E. coli putative transcriptional regulator LYSR-type (AAC75630.1); Blastp hit to AAC75630.1 (308 aa), 78% identity in aa 16 - 305; Belongs to the LysR transcriptional regulatory family.
      
 0.718
ppdB
Prepilin peptidase dependent protein B; Putative component in type IV pilin biogenesis; similar to E. coli prepilin peptidase dependent protein B (AAC75864.1); Blastp hit to AAC75864.1 (187 aa), 67% identity in aa 3 - 187.
      
 0.718
yaiV
Putative inner membrane protein; Involved in oxidative stress resistance.
      
 0.715
yafV
Similar to E. coli putative EC 3.5. amidase-type enzyme (AAC73323.1); Blastp hit to AAC73323.1 (256 aa), 82% identity in aa 3 - 255.
      
 0.679
yegH
Similar to E. coli putative transport protein (AAC75124.1); Blastp hit to AAC75124.1 (549 aa), 90% identity in aa 23 - 549.
      
 0.671
yfeA
Diguanylate cyclase/phosphodiesterase domain 2; similar to E. coli orf, hypothetical protein (AAC75454.1); Blastp hit to AAC75454.1 (768 aa), 68% identity in aa 45 - 766.
      
 0.632
yncC
Putative gntR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC74532.1); Blastp hit to AAC74532.1 (240 aa), 58% identity in aa 20 - 238.
   
  
 0.612
yehS
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75185.1); Blastp hit to AAC75185.1 (156 aa), 90% identity in aa 1 - 155.
   
    0.558
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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