Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yfeHPutative Na+-dependent transporter; Similar to E. coli putative cytochrome oxidase (AAC75463.1); Blastp hit to AAC75463.1 (332 aa), 90% identity in aa 1 - 332. (332 aa)    
Predicted Functional Partners:
yfeR
Similar to E. coli putative transcriptional regulator LYSR-type (AAC75462.1); Blastp hit to AAC75462.1 (308 aa), 79% identity in aa 1 - 308; Belongs to the LysR transcriptional regulatory family.
  
  
 0.979
yiaK
Putative malate dehydrogenase; Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.
   
    0.941
gcd
Similar to E. coli glucose dehydrogenase (AAC73235.1); Blastp hit to AAC73235.1 (796 aa), 92% identity in aa 1 - 796.
  
     0.485
tbpA
Thiamine-binding periplasmic protein; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Is also involved in thiamine pyrophosphate transport.
  
     0.479
yabK
Putative binding-protein-dependent transport system inner membrane component; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Probably responsible for the translocation of the substrate across the membrane (Probable). Is also involved in thiamine pyrophosphate transport.
  
     0.414
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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