Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
amiAN-acetylmuramoyl-l-alanine amidase I; Cell-wall hydrolase involved in septum cleavage during cell division; Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family. (289 aa)    
Predicted Functional Partners:
hemF
Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
 
    0.924
amiB
N-acetylmuramoyl-l-alanine amidase II; Cell-wall hydrolase involved in septum cleavage during cell division.
  
  
 
0.915
amiC
Similar to E. coli putative amidase (AAC75856.1); Blastp hit to AAC75856.1 (447 aa), 94% identity in aa 31 - 446.
  
 
 
0.910
fdnH
Formate dehydrogenase-N, Fe-S beta subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.
      
 0.854
yibP
Similar to E. coli putative membrane protein (AAC76637.1); Blastp hit to AAC76637.1 (427 aa), 91% identity in aa 1 - 427.
 
   0.785
ybdK
Putative cytoplasmic protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
      
 0.764
ypfK
Putative inner membrane protein; Hypothetical protein in eutR-hemF intergenic region (ORF33). (SW:YPFK_SALTY).
       0.709
malE
Maltose transport protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins.
      
 0.595
ycgQ
Putative resistance protein MccF; Homologs of microcin C7; similar to E. coli orf, hypothetical protein (AAC74276.1); Blastp hit to AAC74276.1 (304 aa), 79% identity in aa 1 - 304.
 
  
 0.592
nlpD
Lipoprotein; Activator of the cell wall hydrolase AmiC. Required for septal murein cleavage and daughter cell separation during cell division (By similarity); Belongs to the E.coli NlpD/Haemophilus LppB family.
 
   
 0.586
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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