STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
narQSimilar to E. coli sensor for nitrate reductase system, protein histidine kinase (acts on NarP and narL) (AAC75522.1); Blastp hit to AAC75522.1 (566 aa), 88% identity in aa 3 - 565. (566 aa)    
Predicted Functional Partners:
narP
Response regulator in two-component regulatory system with NarQ (or NarX); Similar to E. coli nitrate/nitrite response regulator (sensor NarQ) (AAC75253.1); Blastp hit to AAC75253.1 (215 aa), 88% identity in aa 1 - 215.
 0.999
narL
Response regulator in two-component regulatory system with NarX (or NarQ); Regulates anaerobic respiration and fermentation (LuxR/UhpA family); similar to E. coli pleiotrophic regulation of anaerobic respiration: response regulator for nar, frd, dms and tor genes (AAC74305.1); Blastp hit to AAC74305.1 (216 aa), 96% identity in aa 1 - 216.
 0.998
csgD
Putative transcriptional regulator; Necessary for transcription of the csgAB operon. May have the capability to respond to starvation and/or high cell density by activating csgBA transcription (By similarity).
 
 
 0.799
uhpA
Response regulator (repressor) in two-component regulatory system wtih UhpB; Part of the UhpABC signaling cascade that controls the expression of the hexose phosphate transporter UhpT. Activates the transcription of the uhpT gene. Acts by binding specifically to the uhpT promoter region.
 
 
 0.791
fimZ
Fimbrial protein Z; Putative transcriptional regulator (LuxR/UhpA family); fimbriae Z protein. (SW:FIMZ_SALTY).
 
 
 0.764
dcuS
Sensory histidine kinase in two-component retgulatory system with DcuR; Senses fumarate/C4-dicarboxylate; similar to E. coli putative 2-component sensor protein (AAC77086.1); Blastp hit to AAC77086.1 (543 aa), 81% identity in aa 1 - 542.
   
  
 0.764
yhjB
LuxR/UhpA family; similar to E. coli putative regulator (AAC76545.1); Blastp hit to AAC76545.1 (200 aa), 72% identity in aa 1 - 200.
 
 
 0.753
ssrB
Secretion system regulator: transcriptonal activator; Homologous with degU/uvrY/bvgA; SsrB (gi|2765824).
 
 
 0.744
uvrY
Putative LuxR/UhpA family response regulator; Similar to E. coli putative 2-component transcriptional regulator (AAC74981.1); Blastp hit to AAC74981.1 (218 aa), 96% identity in aa 1 - 218.
 
 0.712
narK
Similar to E. coli nitrite extrusion protein (AAC74307.1); Blastp hit to AAC74307.1 (463 aa), 94% identity in aa 1 - 462.
  
  
 0.698
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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