STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yffBPutative glutaredoxin family protein; Similar to E. coli orf, hypothetical protein (AAC75524.1); Blastp hit to AAC75524.1 (118 aa), 80% identity in aa 1 - 118; Belongs to the ArsC family. (118 aa)    
Predicted Functional Partners:
dapE
N-succinyl-diaminopimelate deacylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls. Can also hydrolyze all N-terminal Asp dipeptides except Asp-Pro. Asp-Ser is the best substrate, followed by Asp-Gly, Asp-Leu, and Asp- Cys; Belongs to the peptidase M20A family. DapE subfamily.
 
  
 0.948
yggU
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75990.1); Blastp hit to AAC75990.1 (100 aa), 90% identity in aa 5 - 98; Belongs to the UPF0235 family.
      
 0.859
STM3600
Putative sugar kinases; Ribokinase family; similar to E. coli putative kinase (AAC76399.1); Blastp hit to AAC76399.1 (261 aa), 30% identity in aa 7 - 261.
   
  
 0.854
STM4313
Putative cytoplasmic protein.
      
 0.816
yhaH
Putative inner membrane protein; Similar to E. coli putative cytochrome (AAC76138.1); Blastp hit to AAC76138.1 (121 aa), 89% identity in aa 1 - 118.
   
  
 0.814
ypfN
Putative inner membrane protein.
  
    0.732
preT
Putative NADPH-dependent glutamate synthase beta chain or related oxidoreductase; Involved in pyrimidine base degradation. Catalyzes physiologically the reduction of uracil to 5,6-dihydrouracil (DHU) by using NADH as a specific cosubstrate. It also catalyzes the reverse reaction and the reduction of thymine to 5,6-dihydrothymine (DHT) (By similarity).
      
 0.726
ydgH
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74676.1); Blastp hit to AAC74676.1 (314 aa), 90% identity in aa 1 - 314.
      
 0.669
dlhH
Putative dienelactone hydrolase family; Similar to E. coli putative enzyme (AAC76833.1); Blastp hit to AAC76833.1 (332 aa), 91% identity in aa 2 - 181.
      
 0.649
sadB
Putative inner membrane lipoprotein; Required for proper surface expression of the autotransporter adhesin SadA. Could be directly involved in the biogenesis of functionally active SadA.
      
 0.646
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.