Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gcvRSimilar to E. coli transcriptional regulation of gcv operon (AAC75532.1); Blastp hit to AAC75532.1 (212 aa), 88% identity in aa 1 - 212. (212 aa)    
Predicted Functional Partners:
gcvA
Regulator of gcv operon; LysR family; similar to E. coli positive regulator of gcv operon (AAC75850.1); Blastp hit to AAC75850.1 (305 aa), 98% identity in aa 1 - 305; Belongs to the LysR transcriptional regulatory family.
    
 
 0.955
bcp
Thioredoxin dependent thiol peroxidase; Similar to E. coli bacterioferritin comigratory protein (AAC75533.1); Blastp hit to AAC75533.1 (156 aa), 98% identity in aa 1 - 156.
 
    0.949
dppA
Dipeptide transport protein; ABC superfamily (peri_perm); similar to E. coli dipeptide transport protein (AAC76569.1); Blastp hit to AAC76569.1 (535 aa), 93% identity in aa 1 - 535.
   
  
 0.775
ygjU
Putative dicarboxylate permease; Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system). Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
   
  
 0.756
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
    0.748
nlpB
Lipoprotein-34; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
    0.731
cycA
APC family D-alanine/D-serine/glycine transport protein; Similar to E. coli transport of D-alanine, D-serine, and glycine (AAC77165.1); Blastp hit to AAC77165.1 (470 aa), 95% identity in aa 1 - 469.
   
  
 0.708
ybeL
Similar to E. coli putative alpha helical protein (AAC73744.1); Blastp hit to AAC73744.1 (160 aa), 91% identity in aa 1 - 160.
  
     0.699
gcvP
Glycine cleavage complex protein P; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
  
 0.681
purC
SAICAR synthetase; similar to E. coli phosphoribosylaminoimidazole-succinocarboxamide synthetase = SAICAR synthetase (AAC75529.1); Blastp hit to AAC75529.1 (237 aa), 94% identity in aa 1 - 237.
  
    0.670
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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