Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yfgDSimilar to E. coli putative oxidoreductase (AAC75548.1); Blastp hit to AAC75548.1 (119 aa), 83% identity in aa 1 - 119. (119 aa)    
Predicted Functional Partners:
bepA
Putative inner membrane or exported; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
 
  
 0.976
ypfN
Putative inner membrane protein.
  
  
 0.924
pyrD
Dihydro-orotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
      0.868
yliH
Putative cytoplasmic protein; Similar to E. coli putative receptor (AAC73923.1); Blastp hit to AAC73923.1 (127 aa), 78% identity in aa 1 - 124.
   
  
 0.861
STM1790
Putative thiol-disulfide isomerase and thioredoxin; Similar to E. coli processing of HyaA and HyaB proteins (AAC74061.1); Blastp hit to AAC74061.1 (132 aa), 72% identity in aa 1 - 125.
   
  
 0.727
ydhD
Putative glutaredoxin protein; Similar to E. coli orf, hypothetical protein (AAC74726.1); Blastp hit to AAC74726.1 (115 aa), 97% identity in aa 1 - 115; Belongs to the glutaredoxin family. Monothiol subfamily.
   
  
 0.652
perM
Similar to E. coli putative permease (AAC75546.1); Blastp hit to AAC75546.1 (353 aa), 94% identity in aa 1 - 350.
     
 0.571
STM0402
Similar to E. coli alkyl hydroperoxide reductase, C22 subunit; detoxification of hydroperoxides (AAC73706.1); Blastp hit to AAC73706.1 (187 aa), 36% identity in aa 1 - 186.
  
  
 0.564
ypfI
Putative acetyltransferase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
      
 0.512
rpoA
RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.509
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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