| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| STM3334 | deoA | STM3334 | STM4568 | Similar to E. coli cytosine deaminase (AAC73440.1); Blastp hit to AAC73440.1 (427 aa), 83% identity in aa 1 - 427. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.926 |
| STM3334 | udp | STM3334 | STM3968 | Similar to E. coli cytosine deaminase (AAC73440.1); Blastp hit to AAC73440.1 (427 aa), 83% identity in aa 1 - 427. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity). | 0.915 |
| STM3334 | upp | STM3334 | STM2498 | Similar to E. coli cytosine deaminase (AAC73440.1); Blastp hit to AAC73440.1 (427 aa), 83% identity in aa 1 - 427. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.947 |
| STM3334 | yeiA | STM3334 | STM2187 | Similar to E. coli cytosine deaminase (AAC73440.1); Blastp hit to AAC73440.1 (427 aa), 83% identity in aa 1 - 427. | Putative dihydropyrimidine dehydrogenase; Involved in pyrimidine base degradation. Catalyzes physiologically the reduction of uracil to 5,6-dihydrouracil (DHU) by using NADH as a specific cosubstrate. It also catalyzes the reverse reaction and the reduction of thymine to 5,6-dihydrothymine (DHT) (By similarity). | 0.946 |
| deoA | STM3334 | STM4568 | STM3334 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Similar to E. coli cytosine deaminase (AAC73440.1); Blastp hit to AAC73440.1 (427 aa), 83% identity in aa 1 - 427. | 0.926 |
| deoA | guaA | STM4568 | STM2510 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.455 |
| deoA | pyrH | STM4568 | STM0218 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.401 |
| deoA | surE | STM4568 | STM2927 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Survival protein, protein damage control; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs. | 0.952 |
| deoA | udk | STM4568 | STM2122 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Similar to E. coli uridine/cytidine kinase (AAC75127.1); Blastp hit to AAC75127.1 (231 aa), 95% identity in aa 19 - 231. | 0.528 |
| deoA | udp | STM4568 | STM3968 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity). | 0.982 |
| deoA | upp | STM4568 | STM2498 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.956 |
| deoA | yeiA | STM4568 | STM2187 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Putative dihydropyrimidine dehydrogenase; Involved in pyrimidine base degradation. Catalyzes physiologically the reduction of uracil to 5,6-dihydrouracil (DHU) by using NADH as a specific cosubstrate. It also catalyzes the reverse reaction and the reduction of thymine to 5,6-dihydrothymine (DHT) (By similarity). | 0.929 |
| guaA | deoA | STM2510 | STM4568 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.455 |
| guaA | pyrF | STM2510 | STM1707 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.581 |
| guaA | pyrH | STM2510 | STM0218 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.699 |
| guaA | surE | STM2510 | STM2927 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Survival protein, protein damage control; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs. | 0.947 |
| guaA | udk | STM2510 | STM2122 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Similar to E. coli uridine/cytidine kinase (AAC75127.1); Blastp hit to AAC75127.1 (231 aa), 95% identity in aa 19 - 231. | 0.401 |
| guaA | upp | STM2510 | STM2498 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.941 |
| guaA | uraA | STM2510 | STM2497 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | NCS2 family uracil transport protein; Similar to E. coli uracil transport (AAC75550.1); Blastp hit to AAC75550.1 (429 aa), 94% identity in aa 1 - 425. | 0.540 |
| guaA | yeiA | STM2510 | STM2187 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Putative dihydropyrimidine dehydrogenase; Involved in pyrimidine base degradation. Catalyzes physiologically the reduction of uracil to 5,6-dihydrouracil (DHU) by using NADH as a specific cosubstrate. It also catalyzes the reverse reaction and the reduction of thymine to 5,6-dihydrothymine (DHT) (By similarity). | 0.562 |
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