STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ratAPutative outer membrane protein; RatA (gi|4583529). (1865 aa)    
Predicted Functional Partners:
STM0660
Putative cytoplasmic protein.
      
 0.812
STM4200
Similar to E. coli putative membrane protein (AAC74454.1); Blastp hit to AAC74454.1 (1122 aa), 31% identity in aa 312 - 498, 33% identity in aa 426 - 547, 22% identity in aa 233 - 444, 30% identity in aa 132 - 266, 23-1073758628dentity in aa 170 - 398, 21% identity in aa 178 - 417, 24-1073758654dentity in aa 111 - 354, 23% identity in aa 950 - 1104, 20% identity in aa 1015 - 1106.
     
 0.812
sinH
SinH; Similar to Escherichia coli intimin and Yersinia pestis invasin proteins; (gi|4583531).
  
  
 0.784
stiA
Putative fimbrial subunit; Similar to E. coli major type 1 subunit fimbrin (pilin) (AAC77270.1); Blastp hit to AAC77270.1 (182 aa), 37% identity in aa 1 - 181.
   
  
 0.724
sinI
Putative outer membrane protein; SinI (gi|4583530).
  
  
 0.724
yajF
Putative sugar kinase/putative transcriptional regulator (NagC/XylR family); Similar to E. coli possible NAGC-like transcriptional regulator (AAC73497.1); Blastp hit to AAC73497.1 (348 aa), 88% identity in aa 47 - 346.
      
 0.649
ftsK
Cell division protein; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA trans [...]
   
 
 0.584
ratB
Putative outer membrane protein; RatB (gi|5107806).
     
0.502
rnc
RNase III, ds RNA; Digests double-stranded RNA. Involved in the processing of ribosomal RNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Removes small helical intervening sequences (IVSs) from all 7 of the 23S rRNA transcripts. Probably also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Probably processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
    
 
 0.491
caiC
crotonobetaine/carnitine-CoA ligase; Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine.
      
 0.474
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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