sinI protein (Salmonella enterica Typhimurium)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

sinI

Putative outer membrane protein; SinI (gi|4583530). (319 aa)

Predicted Functional Partners:

sinR

0.895

trpL

0.854

sinH

0.728

ratA

0.724

STM1330

0.720

moaC

0.474

trpE

0.451

Your Current Organism:

Salmonella enterica Typhimurium

NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
STM1330	sinI	STM1330	STM2516	Putative DNA/RNA non-specific endonuclease.	Putative outer membrane protein; SinI (gi\|4583530).	0.720
moaC	sinI	STM0804	STM2516	Molybdopterin biosynthesis, protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.	Putative outer membrane protein; SinI (gi\|4583530).	0.474
moaC	trpE	STM0804	STM1723	Molybdopterin biosynthesis, protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.	Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...]	0.476
ratA	sinH	STM2515	STM2517	Putative outer membrane protein; RatA (gi\|4583529).	SinH; Similar to Escherichia coli intimin and Yersinia pestis invasin proteins; (gi\|4583531).	0.784
ratA	sinI	STM2515	STM2516	Putative outer membrane protein; RatA (gi\|4583529).	Putative outer membrane protein; SinI (gi\|4583530).	0.724
sinH	ratA	STM2517	STM2515	SinH; Similar to Escherichia coli intimin and Yersinia pestis invasin proteins; (gi\|4583531).	Putative outer membrane protein; RatA (gi\|4583529).	0.784
sinH	sinI	STM2517	STM2516	SinH; Similar to Escherichia coli intimin and Yersinia pestis invasin proteins; (gi\|4583531).	Putative outer membrane protein; SinI (gi\|4583530).	0.728
sinI	STM1330	STM2516	STM1330	Putative outer membrane protein; SinI (gi\|4583530).	Putative DNA/RNA non-specific endonuclease.	0.720
sinI	moaC	STM2516	STM0804	Putative outer membrane protein; SinI (gi\|4583530).	Molybdopterin biosynthesis, protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.	0.474
sinI	ratA	STM2516	STM2515	Putative outer membrane protein; SinI (gi\|4583530).	Putative outer membrane protein; RatA (gi\|4583529).	0.724
sinI	sinH	STM2516	STM2517	Putative outer membrane protein; SinI (gi\|4583530).	SinH; Similar to Escherichia coli intimin and Yersinia pestis invasin proteins; (gi\|4583531).	0.728
sinI	sinR	STM2516	STM0304	Putative outer membrane protein; SinI (gi\|4583530).	Transcriptional regulator; Probable regulatory protein. Its target is not known.	0.895
sinI	trpE	STM2516	STM1723	Putative outer membrane protein; SinI (gi\|4583530).	Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...]	0.451
sinI	trpL	STM2516	STM1722	Putative outer membrane protein; SinI (gi\|4583530).	Trp operon leader peptide; This protein is involved in control of the biosynthesis of tryptophan.	0.854
sinR	sinI	STM0304	STM2516	Transcriptional regulator; Probable regulatory protein. Its target is not known.	Putative outer membrane protein; SinI (gi\|4583530).	0.895
sinR	trpL	STM0304	STM1722	Transcriptional regulator; Probable regulatory protein. Its target is not known.	Trp operon leader peptide; This protein is involved in control of the biosynthesis of tryptophan.	0.688
trpE	moaC	STM1723	STM0804	Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...]	Molybdopterin biosynthesis, protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.	0.476
trpE	sinI	STM1723	STM2516	Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...]	Putative outer membrane protein; SinI (gi\|4583530).	0.451
trpE	trpL	STM1723	STM1722	Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...]	Trp operon leader peptide; This protein is involved in control of the biosynthesis of tryptophan.	0.566
trpL	sinI	STM1722	STM2516	Trp operon leader peptide; This protein is involved in control of the biosynthesis of tryptophan.	Putative outer membrane protein; SinI (gi\|4583530).	0.854

page 1 of 2

Server load: high (90%) [HD]

Permalink

Network

Neighborhood

Textmining

Co-occurrence

Experiments

Co-expression

Databases

Fusion

© STRING Consortium 2026

Credits

Access

Info

About