Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yfgMPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75566.1); Blastp hit to AAC75566.1 (206 aa), 88% identity in aa 1 - 206. (206 aa)    
Predicted Functional Partners:
hisS
histidyl-tRNA synthetase. (SW:SYH_SALTY).
    0.993
yfgL
Putative serine/threonine protein kinase; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
 0.991
yfgJ
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75563.1); Blastp hit to AAC75563.1 (83 aa), 63% identity in aa 13 - 83.
     
 0.915
nlpB
Lipoprotein-34; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
    0.845
yfgA
Putative membrane protein; Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.
 
    0.835
engA
Putative GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis.
  
  
 0.795
rlpB
A minor lipoprotein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family.
  
  
 0.780
ygfB
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75947.1); Blastp hit to AAC75947.1 (194 aa), 93% identity in aa 1 - 194; Belongs to the UPF0149 family.
  
    0.763
ppdD
Prelipin peptidase dependent protein; Putative major component of type IV pilin; similar to E. coli prelipin peptidase dependent protein (AAC73219.1); Blastp hit to AAC73219.1 (146 aa), 89% identity in aa 1 - 146.
  
     0.747
mreD
Rod shape-determining protein; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.
  
    0.721
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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