STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pbpCTransglycosylase of penicillin-binding protein 1c; Similar to E. coli putative peptidoglycan enzyme (AAC75572.1); Blastp hit to AAC75572.1 (770 aa), 82% identity in aa 7 - 767. (771 aa)    
Predicted Functional Partners:
STM2532
Putative inner membrane lipoprotein; Protects the bacterial cell from host peptidases.
   
 0.999
mrcA
Similar to E. coli peptidoglycan synthetase; penicillin-binding protein 1A (AAC76421.1); Blastp hit to AAC76421.1 (858 aa), 92% identity in aa 1 - 858.
  
 
0.926
mrcB
Transpeptidase of penicillin-binding protein 1b; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
  
  
0.916
bisC
Similar to E. coli biotin sulfoxide reductase (AAC76575.1); Blastp hit to AAC76575.1 (739 aa), 86% identity in aa 2 - 739; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
   
  
 0.894
torA
Trimethylamine N-oxide reductase subunit; Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions.
   
  
 0.828
creD
Similar to E. coli tolerance to colicin E2 (AAC77353.1); Blastp hit to AAC77353.1 (450 aa), 73% identity in aa 1 - 450.
  
     0.628
argC
N-acetyl-gamma-glutamylphosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
     
 0.518
sseA-2
Similar to E. coli putative thiosulfate sulfurtransferase (AAC75574.1); Blastp hit to AAC75574.1 (334 aa), 80% identity in aa 54 - 332.
       0.504
STM2530
Similar to E. coli putative oxidoreductase, major subunit (AAC74660.1); Blastp hit to AAC74660.1 (808 aa), 42% identity in aa 15 - 807; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
    0.500
STM2527
Putative polyferredoxin; Similar to E. coli hydrogenase 4 Fe-S subunit (AAC75541.1); Blastp hit to AAC75541.1 (181 aa), 36% identity in aa 33 - 124, 40% identity in aa 42 - 90.
       0.496
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.