Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cadBAPC family lysine/cadaverine transport protein; Similar to E. coli transport of lysine/cadaverine (AAC77093.1); Blastp hit to AAC77093.1 (444 aa), 90% identity in aa 1 - 440. (443 aa)    
Predicted Functional Partners:
cadC
OmpR family; similar to E. coli transcriptional activator of cad operon (AAC77094.1); Blastp hit to AAC77094.1 (512 aa), 58% identity in aa 1 - 512.
 
   
 0.988
cadA
Lysine decarboxylase, inducible. (SW:DCLY_SALTY); Belongs to the Orn/Lys/Arg decarboxylase class-I family.
 
  
 0.970
speF
Similar to E. coli ornithine decarboxylase isozyme, inducible (AAC73787.1); Blastp hit to AAC73787.1 (732 aa), 91% identity in aa 1 - 732.
 
  
 0.907
adiY
Transcriptional activator of adiA; AraC/XylS family; similar to E. coli putative ARAC-type regulatory protein (AAC77077.1); Blastp hit to AAC77077.1 (253 aa), 79% identity in aa 1 - 253.
      
 0.860
ldcC
Similar to E. coli lysine decarboxylase 2, constitutive (AAC73297.1); Blastp hit to AAC73297.1 (713 aa), 91% identity in aa 1 - 712.
 
   
 0.833
yaeR
Putative lactoylglutathione lyase; Similar to E. coli orf, hypothetical protein (AAC73298.1); Blastp hit to AAC73298.1 (138 aa), 88% identity in aa 10 - 138.
      
 0.815
lysP
Similar to E. coli lysine-specific permease (AAC75217.1); Blastp hit to AAC75217.1 (489 aa), 94% identity in aa 1 - 489.
  
   
 0.708
speC
Similar to E. coli ornithine decarboxylase isozyme (AAC76002.1); Blastp hit to AAC76002.1 (731 aa), 87% identity in aa 21 - 731.
 
   
 0.649
yjdL
Putative POT family, di-/tripeptide transport protein; Similar to E. coli putative peptide transporter (AAC77091.1); Blastp hit to AAC77091.1 (485 aa), 80% identity in aa 1 - 484.
 
   0.638
ompR
Response regulator in two-component regulatory system with EnvZ; Member of the two-component regulatory system EnvZ/OmpR involved in osmoregulation (particularly of genes ompF and ompC) as well as other genes (By similarity). Plays a central role in both acid and osmotic stress responses. Binds to the promoter of both ompC and ompF; at low osmolarity it activates ompF transcription, while at high osmolarity it represses ompF and activates ompC transcription (By similarity).
      
 0.579
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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