Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yfiPPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75636.1); Blastp hit to AAC75636.1 (240 aa), 88% identity in aa 9 - 234. (226 aa)    
Predicted Functional Partners:
yfiQ
Putative acetyl-CoA synthetase; Acetylates and inactivates the acetyl-CoA synthase (Acs). Can also acetylate other central metabolic enzymes in response to environmental changes; In the central section; belongs to the acetate CoA ligase beta subunit family.
 
    0.904
yggH
Putative S-adenosylmethionine-dependent methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
      
 0.854
pssA
Phosphatidylserine synthase; CDP-diacylglycerol-serine O-phosphatidyltransferase; similar to E. coli phosphatidylserine synthase; phospholipid synthesis (AAC75638.1); Blastp hit to AAC75638.1 (452 aa), 93% identity in aa 2 - 452.
      0.776
yecP
Putative enzyme; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
   
  
 0.679
trxC
Similar to E. coli putative thioredoxin-like protein (AAC75635.1); Blastp hit to AAC75635.1 (139 aa), 94% identity in aa 1 - 139; Belongs to the thioredoxin family.
       0.587
ybfE
LexA regulated, putative SOS response; Similar to E. coli orf, hypothetical protein (AAC73779.1); Blastp hit to AAC73779.1 (120 aa), 90% identity in aa 24 - 120.
  
    0.547
smtA
S-adenosylmethionine-dependent methyltransferase; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs; Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
      
 0.539
yrdC
Putative translation factor; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
      
 0.512
yecO
Putative SAM-dependent methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM); Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
     
 0.464
glpG
Protein of glp regulon; Rhomboid-type serine protease that catalyzes intramembrane proteolysis.
 
     0.464
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.