Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
yfjGPutative oligoketide cyclase/lipid transport protein; Similar to E. coli orf, hypothetical protein (AAC75668.1); Blastp hit to AAC75668.1 (158 aa), 88% identity in aa 1 - 157. (158 aa)    
Predicted Functional Partners:
yfjF
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75667.1); Blastp hit to AAC75667.1 (102 aa), 87% identity in aa 7 - 102; Belongs to the UPF0125 (RnfH) family.
 
  
 0.995
ubiG
3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
  
   
 0.694
yeeO
Putative MATE family transport protein; Similar to E. coli orf, hypothetical protein (AAC75048.1); Blastp hit to AAC75048.1 (547 aa), 82% identity in aa 53 - 533.
      
 0.647
smpB
Small protein B; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to tran [...]
  
    0.645
visC
Putative monooxygenase; Similar to E. coli orf, hypothetical protein (AAC75944.1); Blastp hit to AAC75944.1 (400 aa), 87% identity in aa 1 - 400.
  
   
 0.618
ubiA
P-hydroxybenzoate: octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
  
 
 0.606
sspA
Stringent starvation protein A; Regulator of transcription; similar to E. coli regulator of transcription; stringent starvation protein A (AAC76261.1); Blastp hit to AAC76261.1 (212 aa), 98% identity in aa 1 - 211; Belongs to the GST superfamily.
  
     0.600
dnaQ
DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contains the editing function and is a proofreading 3'- 5' exonuclease (By similarity).
  
     0.561
nlpC
Lipoprotein; Similar to E. coli lipoprotein (AAC74778.1); Blastp hit to AAC74778.1 (154 aa), 86% identity in aa 1 - 154.
      
 0.543
ubiF
Putative monooxygenase; Similar to E. coli orf, hypothetical protein (AAC73763.1); Blastp hit to AAC73763.1 (391 aa), 85% identity in aa 1 - 391.
  
   
 0.527
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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