Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
STM2704Fels-2 prophage protein; Similar to genes in P2-like phages; unknown (gi|2852345). (135 aa)    
Predicted Functional Partners:
STM2706
Fels-2 prophage protein; Similar to tail fiber protein in phage P2.
  
  
 0.968
STM2703
Fels-2 prophage protein; Similar to invertase (pin) in phage E14; unknown (gi|2852344).
  
  
 0.964
STM1054
Gifsy-2 prophage protein; Hypothetical protein (gi|5410523).
      
 0.951
STM2769
Similar to E. coli IS3 putative transposase (AAC75150.1); Blastp hit to AAC75150.1 (288 aa), 84% identity in aa 1 - 288.
   
  
 0.854
umuC
Error-prone repair protein; Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template.
      
 0.726
STM2702
Fels-2 prophage protein; Similar to te-specific recombinases; DNA invertase Pin homolog; similar to E. coli inversion of adjacent DNA; at locus of e14 element (AAC74242.1); Blastp hit to AAC74242.1 (184 aa), 88% identity in aa 3 - 180.
  
    0.699
sirC
Regulator of invasion genes; Required for maximal expression of sirC, not required to invade host cells.
      
 0.650
STM0900
Putative Fels-1 prophage DNA or RNA helicases of superfamily II; Similar to E. coli putative ATP-dependent helicase (AAC75245.1); Blastp hit to AAC75245.1 (586 aa), 29% identity in aa 124 - 378, 25% identity in aa 20 - 158.
   
    0.643
STM2701
Fels-2 prophage protein; Similar to tail sheath proteins in phage P2.
  
  
 0.633
STM0921
Putative Fels-1 prophage minor tail protein.
  
    0.632
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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