STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STM2730Fels-2 prophage protein; Similar to retron in E coli; similar to E. coli DNA adenine methylase (AAC76412.1); Blastp hit to AAC76412.1 (278 aa), 46% identity in aa 8 - 266. (285 aa)    
Predicted Functional Partners:
STM2729
Fels-2 prophage protein; Possible endonuclease which induces a single-strand cut and initiates DNA replication.
  
  
 0.981
STM2724
Fels-2 prophage protein.
  
  
 0.940
STM2731
Fels-2 prophage protein; Similar to protein in phage 186; similar to E. coli orf, hypothetical protein (AAC73890.1); Blastp hit to AAC73890.1 (88 aa), 42% identity in aa 9 - 76.
  
    0.924
mutH
Methyl-directed mismatch repair protein; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair; Belongs to the MutH family.
 
   
 0.909
dam
DNA adenine methylase; Methylates DNA within the sequence GATC and protects the DNA from cleavage by the restriction endonuclease MboI. Although it shares sequence specificity with a number of type II restriction endonucleases and methylases, it is thought to act in postreplication mismatch repair rather than as a part of a restriction modification system. May also play a role in DNA replication; Belongs to the N(4)/N(6)-methyltransferase family.
  
  
 
0.907
STM2703
Fels-2 prophage protein; Similar to invertase (pin) in phage E14; unknown (gi|2852344).
  
    0.903
STM2722
Fels-2 prophage protein; Similar to gpP; ATP charging in phage P2.
  
  
 0.899
STM2733
Fels-2 prophage protein; Similar to E. coli retron Ec67.
  
    0.889
STM2732
Fels-2 prophage protein; Similar to protein in phage 186.
  
    0.871
STM2739
Fels-2 prophage protein; Similar to int protein in phage 186; similar to E. coli prophage DLP12 integrase (AAC73638.1); Blastp hit to AAC73638.1 (387 aa), 41% identity in aa 302 - 363, 24% identity in aa 66 - 280, 35% identity in aa 19 - 50.
   
  
 0.868
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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