Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
STM2767Putative superfamily I DNA and RNA helicase. (660 aa)    
Predicted Functional Partners:
STM2746
Putative excinuclease ATPase subunit.
   
  
 0.992
STM2766
Putative cytoplasmic protein.
  
    0.945
STM2761
Putative inner membrane protein.
   
  
 0.921
uvrD
DNA-dependent ATPase I and helicase II; Has both ATPase and helicase activities. Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present. Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair; Belongs to the helicase family. UvrD subfamily.
    
  0.902
STM2759
Putative dipeptide/oligopeptide/nickel ABC-type transport systems, periplasmic component; Similar to E. coli putative transport protein (AAC73180.1); Blastp hit to AAC73180.1 (551 aa), 27% identity in aa 19 - 545.
   
  
 0.898
STM2753
Similar to E. coli putative dehydrogenase (AAC74397.1); Blastp hit to AAC74397.1 (351 aa), 30% identity in aa 10 - 151, 28% identity in aa 312 - 346.
   
  
 0.870
STM2760
Putative integrase; Belongs to the 'phage' integrase family.
   
  
 0.855
STM0929
Putative inner membrane protein.
   
  
 0.770
STM0893
Putative Fels-1 prophage integrase; Similar to E. coli putative transposase (AAC74651.1); Blastp hit to AAC74651.1 (398 aa), 55% identity in aa 2 - 398; Belongs to the 'phage' integrase family.
      
 0.769
hin
H inversion protein; A DNA fragment of approximately 900 base pairs, adjacent to the fljB (H2) gene, which specifies the synthesis of phase-2 flagellin, can exist in either orientation with respect to fljB. The orientation of the inversion region controls expression of fljB. The hin gene occupies about two-thirds of the inversion region; it is required for the inversion of the fljB controlling region.
   
  
 0.728
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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