Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fljARepressor of fliC; Transcriptional repressor of the FliC phase-1 flagellin. (179 aa)    
Predicted Functional Partners:
fljB
Filament structural protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
  
  
 0.980
hin
H inversion protein; A DNA fragment of approximately 900 base pairs, adjacent to the fljB (H2) gene, which specifies the synthesis of phase-2 flagellin, can exist in either orientation with respect to fljB. The orientation of the inversion region controls expression of fljB. The hin gene occupies about two-thirds of the inversion region; it is required for the inversion of the fljB controlling region.
  
  
 0.973
fliC
Flagellar biosynthesis; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
   
  
 0.897
STM2757
Putative cytoplasmic protein.
      
 0.860
iroB
Putative glycosyl transferase; Related to UDP-glucuronosyltransferase.
      
 0.854
fliB
N-methylation of lysine residues in flagellin; Post-translationally modifies flagellin by methylation of epsilon amino group of surface-exposed lysine residues.
   
  
 0.853
STM2761
Putative inner membrane protein.
   
  
 0.853
STM2740
Fels-2 prophage protein; Similar to int protein in phage CP4-57; similar to E. coli prophage CP4-57 integrase (AAC75670.1); Blastp hit to AAC75670.1 (413 aa), 47% identity in aa 1 - 341; Belongs to the 'phage' integrase family.
   
  
 0.791
STM2758
Putative phosphotransferase system IIC component; Similar to E. coli PTS system, glucose-specific IIBC component (AAC74185.1); Blastp hit to AAC74185.1 (477 aa), 44% identity in aa 44 - 477, 42% identity in aa 4 - 93.
      
 0.770
STM2760
Putative integrase; Belongs to the 'phage' integrase family.
   
  
 0.769
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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