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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ygaEPutative GntR family transcriptional repressor; Similar to E. coli putative transcriptional regulator (AAC75711.1); Blastp hit to AAC75711.1 (226 aa), 87% identity in aa 10 - 225. (225 aa)    
Predicted Functional Partners:
ygaF
Putative sarcosine oxidase-like protein; Catalyzes the dehydrogenation of L-2-hydroxyglutarate (L2HG) to alpha-ketoglutarate and couples to the respiratory chain by feeding electrons from the reaction into the membrane quinone pool. Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. Reaction=(S)-2-hydroxyglutarate + a quinone = 2-oxoglutarate + a quinol; Xref=Rhea:RHEA:58664, ChEBI:CHEBI:16782, ChEBI:CHEBI:16810, ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:58665; Belongs to the L2 [...]
 
  
 0.735
gabP
APC family; similar to E. coli transport permease protein of gamma-aminobutyrate (AAC75710.1); Blastp hit to AAC75710.1 (466 aa), 92% identity in aa 1 - 466.
  
  
 0.725
STM2275
Putative gntR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC74613.1); Blastp hit to AAC74613.1 (228 aa), 25% identity in aa 13 - 217.
  
     0.719
STM3357
Putative gntR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC74613.1); Blastp hit to AAC74613.1 (228 aa), 23% identity in aa 15 - 214.
  
     0.717
ydfH
Putative gntR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC74613.1); Blastp hit to AAC74613.1 (228 aa), 86% identity in aa 1 - 228.
  
     0.690
yncC
Putative gntR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC74532.1); Blastp hit to AAC74532.1 (240 aa), 58% identity in aa 20 - 238.
  
     0.619
STM3358
Putative gntR family regulatory protein.
  
     0.602
yieP
Putative gntR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC76778.1); Blastp hit to AAC76778.1 (181 aa), 82% identity in aa 1 - 181.
  
  
 0.546
gabT
Similar to E. coli 4-aminobutyrate aminotransferase activity (AAC75709.1); Blastp hit to AAC75709.1 (426 aa), 88% identity in aa 1 - 426; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 0.515
lldR
Putative transcriptional GntR family regulator for lct operon; Similar to E. coli transcriptional regulator (AAC76628.1); Blastp hit to AAC76628.1 (258 aa), 86% identity in aa 1 - 258.
  
  
 0.508
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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