| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| STM2797 | copA | STM2797 | STM0498 | Putative arsR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC75714.1); Blastp hit to AAC75714.1 (99 aa), 89% identity in aa 1 - 99. | Putative copper-transporting ATPase; [Copper-exporting P-type ATPase]: Involved in Cu(+) export (By similarity). Essential for copper tolerance under both aerobic and anaerobic conditions. | 0.637 |
| STM2797 | nadR | STM2797 | STM4580 | Putative arsR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC75714.1); Blastp hit to AAC75714.1 (99 aa), 89% identity in aa 1 - 99. | Trifunctional protein; This enzyme has three activities: DNA binding, nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The DNA-binding domain binds to the nadB operator sequence in an NAD- and ATP-dependent manner. As NAD levels increase within the cell, the affinity of NadR for the nadB operator regions of nadA, nadB, and pncB increases, repressing the transcription of these genes. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the A [...] | 0.410 |
| STM2797 | nifJ | STM2797 | STM1651 | Putative arsR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC75714.1); Blastp hit to AAC75714.1 (99 aa), 89% identity in aa 1 - 99. | Similar to E. coli putative oxidoreductase, Fe-S subunit (AAC74460.1); Blastp hit to AAC74460.1 (1174 aa), 92% identity in aa 1 - 1174. | 0.547 |
| STM2797 | ybiR | STM2797 | STM0836 | Putative arsR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC75714.1); Blastp hit to AAC75714.1 (99 aa), 89% identity in aa 1 - 99. | Putative di- and tricarboxylate transporters; Similar to E. coli orf, hypothetical protein (AAC73905.1); Blastp hit to AAC73905.1 (372 aa), 83% identity in aa 1 - 370. | 0.448 |
| STM2797 | ybjZ | STM2797 | STM0942 | Putative arsR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC75714.1); Blastp hit to AAC75714.1 (99 aa), 89% identity in aa 1 - 99. | Putative ABC superfamily (atp&memb) transport protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.413 |
| STM2797 | yeiA | STM2797 | STM2187 | Putative arsR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC75714.1); Blastp hit to AAC75714.1 (99 aa), 89% identity in aa 1 - 99. | Putative dihydropyrimidine dehydrogenase; Involved in pyrimidine base degradation. Catalyzes physiologically the reduction of uracil to 5,6-dihydrouracil (DHU) by using NADH as a specific cosubstrate. It also catalyzes the reverse reaction and the reduction of thymine to 5,6-dihydrothymine (DHT) (By similarity). | 0.417 |
| STM2797 | ygaP | STM2797 | STM2798 | Putative arsR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC75714.1); Blastp hit to AAC75714.1 (99 aa), 89% identity in aa 1 - 99. | Putative rhodanese-related sulfurtransferase; Similar to E. coli orf, hypothetical protein (AAC75715.1); Blastp hit to AAC75715.1 (174 aa), 75% identity in aa 1 - 173. | 0.935 |
| STM2797 | ygaU | STM2797 | STM2795 | Putative arsR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC75714.1); Blastp hit to AAC75714.1 (99 aa), 89% identity in aa 1 - 99. | Putative LysM domain protein; Similar to E. coli orf, hypothetical protein (AAC75712.1); Blastp hit to AAC75712.1 (149 aa), 93% identity in aa 1 - 149. | 0.426 |
| STM2797 | yqaE | STM2797 | STM2796 | Putative arsR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC75714.1); Blastp hit to AAC75714.1 (99 aa), 89% identity in aa 1 - 99. | Putative YqaE family transport protein; Similar to E. coli orf, hypothetical protein (AAC75713.1); Blastp hit to AAC75713.1 (52 aa), 94% identity in aa 1 - 51. | 0.515 |
| copA | STM2797 | STM0498 | STM2797 | Putative copper-transporting ATPase; [Copper-exporting P-type ATPase]: Involved in Cu(+) export (By similarity). Essential for copper tolerance under both aerobic and anaerobic conditions. | Putative arsR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC75714.1); Blastp hit to AAC75714.1 (99 aa), 89% identity in aa 1 - 99. | 0.637 |
| copA | nifJ | STM0498 | STM1651 | Putative copper-transporting ATPase; [Copper-exporting P-type ATPase]: Involved in Cu(+) export (By similarity). Essential for copper tolerance under both aerobic and anaerobic conditions. | Similar to E. coli putative oxidoreductase, Fe-S subunit (AAC74460.1); Blastp hit to AAC74460.1 (1174 aa), 92% identity in aa 1 - 1174. | 0.695 |
| copA | yeiA | STM0498 | STM2187 | Putative copper-transporting ATPase; [Copper-exporting P-type ATPase]: Involved in Cu(+) export (By similarity). Essential for copper tolerance under both aerobic and anaerobic conditions. | Putative dihydropyrimidine dehydrogenase; Involved in pyrimidine base degradation. Catalyzes physiologically the reduction of uracil to 5,6-dihydrouracil (DHU) by using NADH as a specific cosubstrate. It also catalyzes the reverse reaction and the reduction of thymine to 5,6-dihydrothymine (DHT) (By similarity). | 0.418 |
| nadR | STM2797 | STM4580 | STM2797 | Trifunctional protein; This enzyme has three activities: DNA binding, nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The DNA-binding domain binds to the nadB operator sequence in an NAD- and ATP-dependent manner. As NAD levels increase within the cell, the affinity of NadR for the nadB operator regions of nadA, nadB, and pncB increases, repressing the transcription of these genes. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the A [...] | Putative arsR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC75714.1); Blastp hit to AAC75714.1 (99 aa), 89% identity in aa 1 - 99. | 0.410 |
| nifJ | STM2797 | STM1651 | STM2797 | Similar to E. coli putative oxidoreductase, Fe-S subunit (AAC74460.1); Blastp hit to AAC74460.1 (1174 aa), 92% identity in aa 1 - 1174. | Putative arsR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC75714.1); Blastp hit to AAC75714.1 (99 aa), 89% identity in aa 1 - 99. | 0.547 |
| nifJ | copA | STM1651 | STM0498 | Similar to E. coli putative oxidoreductase, Fe-S subunit (AAC74460.1); Blastp hit to AAC74460.1 (1174 aa), 92% identity in aa 1 - 1174. | Putative copper-transporting ATPase; [Copper-exporting P-type ATPase]: Involved in Cu(+) export (By similarity). Essential for copper tolerance under both aerobic and anaerobic conditions. | 0.695 |
| nifJ | ybjZ | STM1651 | STM0942 | Similar to E. coli putative oxidoreductase, Fe-S subunit (AAC74460.1); Blastp hit to AAC74460.1 (1174 aa), 92% identity in aa 1 - 1174. | Putative ABC superfamily (atp&memb) transport protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.457 |
| nifJ | yeiA | STM1651 | STM2187 | Similar to E. coli putative oxidoreductase, Fe-S subunit (AAC74460.1); Blastp hit to AAC74460.1 (1174 aa), 92% identity in aa 1 - 1174. | Putative dihydropyrimidine dehydrogenase; Involved in pyrimidine base degradation. Catalyzes physiologically the reduction of uracil to 5,6-dihydrouracil (DHU) by using NADH as a specific cosubstrate. It also catalyzes the reverse reaction and the reduction of thymine to 5,6-dihydrothymine (DHT) (By similarity). | 0.996 |
| nifJ | ygaU | STM1651 | STM2795 | Similar to E. coli putative oxidoreductase, Fe-S subunit (AAC74460.1); Blastp hit to AAC74460.1 (1174 aa), 92% identity in aa 1 - 1174. | Putative LysM domain protein; Similar to E. coli orf, hypothetical protein (AAC75712.1); Blastp hit to AAC75712.1 (149 aa), 93% identity in aa 1 - 149. | 0.505 |
| ybiR | STM2797 | STM0836 | STM2797 | Putative di- and tricarboxylate transporters; Similar to E. coli orf, hypothetical protein (AAC73905.1); Blastp hit to AAC73905.1 (372 aa), 83% identity in aa 1 - 370. | Putative arsR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC75714.1); Blastp hit to AAC75714.1 (99 aa), 89% identity in aa 1 - 99. | 0.448 |
| ybjZ | STM2797 | STM0942 | STM2797 | Putative ABC superfamily (atp&memb) transport protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Putative arsR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC75714.1); Blastp hit to AAC75714.1 (99 aa), 89% identity in aa 1 - 99. | 0.413 |
