STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
alaEPutative inner membrane protein; Exports L-alanine; Belongs to the AlaE exporter family. (149 aa)    
Predicted Functional Partners:
yahN
Putative transport protein; Similar to E. coli putative cytochrome subunit of dehydrogenase (AAC73431.1); Blastp hit to AAC73431.1 (223 aa), 86% identity in aa 14 - 223.
      
 0.769
yhaO
Similar to E. coli putative transport system permease protein (AAC76145.1); Blastp hit to AAC76145.1 (425 aa), 97% identity in aa 3 - 425.
      
 0.725
yohC
Putative transport protein; Similar to E. coli orf, hypothetical protein (AAC75196.1); Blastp hit to AAC75196.1 (203 aa), 91% identity in aa 9 - 203.
      
 0.720
yjcB
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC77030.1); Blastp hit to AAC77030.1 (116 aa), 83% identity in aa 24 - 116.
   
  
 0.720
rhtC
RhtB family threonine efflux protein; Conducts the efflux of threonine; Belongs to the Rht family.
      
 0.695
tdcB
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. TdcB also dehydrates serine to yield pyruv [...]
      
 0.649
ydeD
Putative permease, integral membrane protein; May be an export pump for several amino acids and their metabolites, including cysteine; Belongs to the EamA transporter family.
      
 0.542
yaaJ
AGCS family; similar to E. coli inner membrane transport protein (AAC73118.1); Blastp hit to AAC73118.1 (476 aa), 76% identity in aa 1 - 476.
      
 0.540
yhcQ
Putative membrane located multidrug resistance protein; Forms an efflux pump with AaeB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
      
 0.517
rthB
Homoserine/homoserine lactone efflux protein; Conducts the efflux of homoserine and homoserine lactone. Belongs to the Rht family.
      
 0.517
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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