Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
proWGlycine/betaine/proline transport protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (354 aa)    
Predicted Functional Partners:
proV
Glycine/betaine/proline transport protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Probably responsible for energy coupling to the transport system.
 0.999
proX
Glycine/betaine/proline transport protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Binds glycine betaine and proline betaine with high affinity.
 
 0.999
osmX
Putative periplasmic component; Part of the OsmU ABC transporter complex, which is involved in the uptake of osmoprotectants such as choline-O-sulfate and glycine betaine.
 
 
 0.951
yehZ
Putative ABC superfamily transport protein (bind_prot); Possibly glycine betaine choline transport for osmoprotection; similar to E. coli putative transport system permease protein (AAC75192.1); Blastp hit to AAC75192.1 (305 aa), 88% identity in aa 1 - 305.
 
 
 0.950
znuC
ABC superfamily high affinity Zn transport protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system (Probable). Seems to be important for the virulence.
     
 0.906
sitB
Fur regulated Salmonella iron transporter; SitB (gi|5231095).
     
 0.906
yjgQ
Putative permease; Similar to E. coli orf, hypothetical protein (AAC77219.1); Blastp hit to AAC77219.1 (361 aa), 97% identity in aa 2 - 361.
   
 
  0.902
yjgP
Putative permease; Similar to E. coli orf, hypothetical protein (AAC77218.1); Blastp hit to AAC77218.1 (366 aa), 94% identity in aa 1 - 366.
   
 
  0.901
modF
Putative ABC superfamily (atp_bind), molybdenum transporter; Similar to E. coli ATP-binding component of molybdate transport system (AAC73847.1); Blastp hit to AAC73847.1 (490 aa), 31% identity in aa 1 - 211.
     
  0.900
btuD
Vitamin B12 transport protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.
     
  0.900
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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