STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
srlAOne of two IIC components; similar to E. coli PTS system, glucitol/sorbitol-specific IIC component, one of two (AAC75744.1); Blastp hit to AAC75744.1 (187 aa), 96% identity in aa 1 - 187. (187 aa)    
Predicted Functional Partners:
srlE
One of two IIC components; similar to E. coli PTS system, glucitol/sorbitol-specific IIB component and second of two IIC components (AAC75745.1); Blastp hit to AAC75745.1 (319 aa), 92% identity in aa 1 - 319.
 
 0.999
slrB
Similar to E. coli PTS system, glucitol/sorbitol-specific enzyme IIA component (AAC75746.1); Blastp hit to AAC75746.1 (123 aa), 82% identity in aa 1 - 118.
 
  0.999
srlD
Similar to E. coli glucitol (sorbitol)-6-phosphate dehydrogenase (AAC75747.1); Blastp hit to AAC75747.1 (259 aa), 97% identity in aa 1 - 259; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  0.998
STM2752
Putative PTS enzyme III glucitol; Similar to E. coli PTS system, glucitol/sorbitol-specific IIB component and second of two IIC components (AAC75745.1); Blastp hit to AAC75745.1 (319 aa), 45% identity in aa 1 - 314.
 
 0.992
STM2751
Similar to E. coli PTS system, glucitol/sorbitol-specific enzyme IIA component (AAC75746.1); Blastp hit to AAC75746.1 (123 aa), 41% identity in aa 3 - 107.
 
 
  0.991
gutM
Putative glucitol (srl) operon regulatory protein; Similar to E. coli glucitol operon activator (AAC75748.1); Blastp hit to AAC75748.1 (119 aa), 83% identity in aa 1 - 119.
 
  
 0.976
STM3256
Putative phosphotransferase system mannitol/fructose-specific IIA domain protein; Similar to E. coli PTS system, fructose-specific IIA/fpr component (AAC75230.1); Blastp hit to AAC75230.1 (376 aa), 52% identity in aa 3 - 141, 41% identity in aa 197 - 374.
 
  
  0.928
STM2750
Similar to E. coli PTS system, glucitol/sorbitol-specific IIC component, one of two (AAC75744.1); Blastp hit to AAC75744.1 (187 aa), 40% identity in aa 9 - 162.
  
  
 
0.909
ptsH
Phosphohistidinoprotein-hexose phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
    
  0.901
STM3779
Putative phosphotransferase system; HPr-related protein; similar to E. coli PTS system protein HPr (AAC75468.1); Blastp hit to AAC75468.1 (85 aa), 28% identity in aa 1 - 83.
    
  0.901
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.