Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
srlRDeoR family; similar to E. coli regulator for gut (srl), glucitol operon (AAC75749.1); Blastp hit to AAC75749.1 (257 aa), 94% identity in aa 1 - 257. (257 aa)    
Predicted Functional Partners:
gutQ
Putative polysialic acid capsule expression protein; Catalyzes the reversible aldol-ketol isomerization between D- ribulose 5-phosphate (Ru5P) and D-arabinose 5-phosphate (A5P). It is also able of sustaining the biosynthetic pathway of 3-deoxy-D-manno- octulosonate (KDO), a unique 8-carbon sugar component of lipopolysaccharides (LPSs) (By similarity).
  
  
 0.983
gutM
Putative glucitol (srl) operon regulatory protein; Similar to E. coli glucitol operon activator (AAC75748.1); Blastp hit to AAC75748.1 (119 aa), 83% identity in aa 1 - 119.
 
  
 0.932
srlD
Similar to E. coli glucitol (sorbitol)-6-phosphate dehydrogenase (AAC75747.1); Blastp hit to AAC75747.1 (259 aa), 97% identity in aa 1 - 259; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 0.928
yjfR
Putative Zn-dependent hydrolases of the beta-lactamase fold; Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3- keto-L-gulonate-6-P. Is essential for L-ascorbate utilization under anaerobic conditions; Belongs to the UlaG family.
     
 0.728
spf
Spot 42 RNA, inhibition of DNA synthesis.
      
 0.674
slrB
Similar to E. coli PTS system, glucitol/sorbitol-specific enzyme IIA component (AAC75746.1); Blastp hit to AAC75746.1 (123 aa), 82% identity in aa 1 - 118.
 
  
 0.671
hydN
Similar to E. coli involved in electron transport from formate to hydrogen, Fe-S centers (AAC75755.1); Blastp hit to AAC75755.1 (175 aa), 95% identity in aa 1 - 173.
      
 0.619
srlA
One of two IIC components; similar to E. coli PTS system, glucitol/sorbitol-specific IIC component, one of two (AAC75744.1); Blastp hit to AAC75744.1 (187 aa), 96% identity in aa 1 - 187.
 
    0.615
mltB
Similar to E. coli membrane-bound lytic murein transglycosylase B (AAC75743.1); Blastp hit to AAC75743.1 (361 aa), 92% identity in aa 1 - 361.
     
 0.584
srlE
One of two IIC components; similar to E. coli PTS system, glucitol/sorbitol-specific IIB component and second of two IIC components (AAC75745.1); Blastp hit to AAC75745.1 (319 aa), 92% identity in aa 1 - 319.
 
    0.569
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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