Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hycEPart of FHL complex; similar to E. coli large subunit of hydrogenase 3 (part of FHL complex) (AAC75763.1); Blastp hit to AAC75763.1 (569 aa), 97% identity in aa 1 - 569. (569 aa)    
Predicted Functional Partners:
hycG
Similar to E. coli hydrogenase activity (AAC75761.1); Blastp hit to AAC75761.1 (255 aa), 96% identity in aa 1 - 255.
 0.999
hycF
Hydrogenase 3; Similar to E. coli probable iron-sulfur protein of hydrogenase 3 (part of FHL complex) (AAC75762.1); Blastp hit to AAC75762.1 (180 aa), 96% identity in aa 1 - 178; putative quinone oxidoreductase.
 
 0.999
hycD
Hydrogenase 3, membrane subunit; Part of FHL complex; similar to E. coli membrane-spanning protein of hydrogenase 3 (part of FHL complex) (AAC75764.1); Blastp hit to AAC75764.1 (307 aa), 90% identity in aa 1 - 307.
 
 0.999
hycC
Hydrogenase 3, membrane subunit; Part of FHL complex; similar to E. coli membrane-spanning protein of hydrogenase 3 (part of FHL complex) (AAC75765.1); Blastp hit to AAC75765.1 (608 aa), 88% identity in aa 1 - 608.
 
 0.999
hycB
Hydrogenase-3, iron-sulfur subunit; Part of FHL complex; similar to E. coli probable small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) (AAC75766.1); Blastp hit to AAC75766.1 (203 aa), 95% identity in aa 1 - 202.
 
 0.999
fdhF
Formate dehydrogenase; Similar to E. coli selenopolypeptide subunit of formate dehydrogenase H (AAD13462.1); Blastp hit to AAD13462.1 (715 aa), 97% identity in aa 1 - 714; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 0.998
hycI
Similar to E. coli protease involved in processing C-terminal end of the large subunit of hydrogenase 3 (AAC75759.1); Blastp hit to AAC75759.1 (156 aa), 91% identity in aa 1 - 155.
 
  
 0.995
hypB
Hydrogenase-3 accessory protein; Assembly of metallocenter; similar to E. coli guanine-nucleotide binding protein, functions as nickel donor for large subunit of hydrogenase 3 (AAC75769.1); Blastp hit to AAC75769.1 (290 aa), 94% identity in aa 1 - 290.
 
 
 
 0.979
hycA
Similar to E. coli transcriptional repression of hyc and hyp operons (AAC75767.1); Blastp hit to AAC75767.1 (153 aa), 88% identity in aa 1 - 152.
  
  
 0.964
nifJ
Similar to E. coli putative oxidoreductase, Fe-S subunit (AAC74460.1); Blastp hit to AAC74460.1 (1174 aa), 92% identity in aa 1 - 1174.
  
 
 0.946
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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