Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ygbAPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75774.1); Blastp hit to AAC75774.1 (117 aa), 86% identity in aa 1 - 114. (114 aa)    
Predicted Functional Partners:
ytfE
Putative cell morphogenesis; Di-iron-containing protein involved in the repair of iron- sulfur clusters damaged by oxidative and nitrosative stress conditions.
  
  
 0.901
yoaG
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74866.1); Blastp hit to AAC74866.1 (60 aa), 96% identity in aa 1 - 60.
   
  
 0.897
STM1808
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74867.1); Blastp hit to AAC74867.1 (119 aa), 42% identity in aa 2 - 113.
      
 0.895
hcr
NADH oxidoreductase for hcp gene product; Similar to E. coli putative enzyme (AAC73959.1); Blastp hit to AAC73959.1 (322 aa), 90% identity in aa 1 - 322.
   
  
 0.853
tehA
K+-tellurite ethidium and proflavin transport protein; TDT family; similar to E. coli tellurite resistance (AAC74511.1); Blastp hit to AAC74511.1 (330 aa), 88% identity in aa 2 - 329.
  
   
 0.812
yjeB
Putative negative regulator; Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity. Represses hmp expression under conditions of elevated intracellular iron concentrations, in the absence of nitric oxide.
      
 0.755
yfhH
Putative ABC superfamily transport protein; Membrane; similar to E. coli orf, hypothetical protein (AAC75614.1); Blastp hit to AAC75614.1 (306 aa), 83% identity in aa 25 - 306.
   
  
 0.745
hmpA
Dihydropteridine reductase 2; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress. Belongs to the globin family. Two-domain flavohemoproteins subfamily.
   
  
 0.728
ygbK
Putative tRNA synthase; Catalyzes the ATP-dependent phosphorylation of 3-oxo- tetronate to 3-oxo-tetronate 4-phosphate. Belongs to the four-carbon acid sugar kinase family.
      
 0.720
yeaR
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74867.1); Blastp hit to AAC74867.1 (119 aa), 83% identity in aa 1 - 119.
   
  
 0.680
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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