STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sitBFur regulated Salmonella iron transporter; SitB (gi|5231095). (273 aa)    
Predicted Functional Partners:
sitA
Fur regulated Salmonella iron transporter; SitA (gi|5231094); Belongs to the bacterial solute-binding protein 9 family.
 
 
 0.999
sitC
Fur regulated Salmonella iron transporter; SitC (gi|5231096).
 0.999
sitD
Fur regulated Salmonella iron transporter; SitD (gi|5231097).
 0.999
znuB
ABC superfamily high affinity Zn transport protein; ATP-binding protein; similar to E. coli orf, hypothetical protein (AAC74929.1); Blastp hit to AAC74929.1 (261 aa), 96% identity in aa 1 - 261.
 
 0.904
znuA
ABC superfamily high affinity Zn transport protein; Binding protein; similar to E. coli putative adhesin (AAC74927.1); Blastp hit to AAC74927.1 (328 aa), 85% identity in aa 1 - 328.
 
  
 0.832
STM1263
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75039.1); Blastp hit to AAC75039.1 (216 aa), 71% identity in aa 3 - 216.
 
  
 0.740
mntR
Putative Mn-dependent transcriptional regulator; In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP (By similarity). Belongs to the DtxR/MntR family.
  
  
 0.609
exbB
Uptake of enterochelin; Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity).
   
  
 0.590
btuD
Vitamin B12 transport protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.
  
  
 
0.587
cboQ
Synthesis of vitamin B12 adenosyl cobalamide precursor; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity; Belongs to the CbiQ family.
     
 0.574
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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