Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sitDFur regulated Salmonella iron transporter; SitD (gi|5231097). (282 aa)    
Predicted Functional Partners:
sitA
Fur regulated Salmonella iron transporter; SitA (gi|5231094); Belongs to the bacterial solute-binding protein 9 family.
 
 0.999
sitB
Fur regulated Salmonella iron transporter; SitB (gi|5231095).
 0.999
sitC
Fur regulated Salmonella iron transporter; SitC (gi|5231096).
 
 
0.999
znuC
ABC superfamily high affinity Zn transport protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system (Probable). Seems to be important for the virulence.
 0.952
znuA
ABC superfamily high affinity Zn transport protein; Binding protein; similar to E. coli putative adhesin (AAC74927.1); Blastp hit to AAC74927.1 (328 aa), 85% identity in aa 1 - 328.
 
  
 0.864
STM3754
Pathogenicity island encoded protein: SPI3; putative ATP binding protein SugR (gi|4324607).
      
 0.649
STM1263
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75039.1); Blastp hit to AAC75039.1 (216 aa), 71% identity in aa 3 - 216.
  
  
 0.628
iroD
Enterochelin esterase-like protein (Fes); Similar to E. coli enterochelin esterase (AAC73686.1); Blastp hit to AAC73686.1 (374 aa), 31% identity in aa 3 - 362.
   
  
 0.587
mntR
Putative Mn-dependent transcriptional regulator; In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP (By similarity). Belongs to the DtxR/MntR family.
  
  
 0.567
iroC
Putative ATP binding cassette (ABC) transporter; Similar to E. coli ATP-binding transport protein; multicopy suppressor of htrB (AAC74000.1); Blastp hit to AAC74000.1 (582 aa), 26% identity in aa 14 - 582, 29% identity in aa 34 - 565.
   
  
 0.562
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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