node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
araC | barA | STM0104 | STM2958 | Transcriptional regulator (AraC/XylS family) for ara operon; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose. | Sensory histidine kinase; Similar to E. coli sensor-regulator, activates OmpR by phophorylation (AAC75828.1); Blastp hit to AAC75828.1 (918 aa), 90% identity in aa 1 - 918. | 0.496 |
araC | fliZ | STM0104 | STM1955 | Transcriptional regulator (AraC/XylS family) for ara operon; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose. | Putative regulator of FliA; May regulate sigma factor activity. | 0.713 |
araC | hilD | STM0104 | STM2875 | Transcriptional regulator (AraC/XylS family) for ara operon; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose. | Regulatory helix-turn-helix proteins, araC family; HilD (gi|4455108). | 0.947 |
araC | invF | STM0104 | STM2899 | Transcriptional regulator (AraC/XylS family) for ara operon; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose. | Invasion protein; Transcriptional regulator required for the expression of several genes encoding type III secretion system SPI1 effector proteins. The interaction with SicA is necessary for the activation of sigDE (sopB pipC), sicAsipBCDA, and sopE. | 0.895 |
araC | sicA | STM0104 | STM2886 | Transcriptional regulator (AraC/XylS family) for ara operon; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose. | Surface presentation of antigens; Type III secretion-associated chaperone required for SipB and SipC stabilization. Prevents premature association of SipB with SipC, which may lead to their targeting for degradation. Along with InvF, required for transcription activation of sigDE (sopB pipC), sicAsipBCDA, and sopE. | 0.700 |
araC | sprB | STM0104 | STM2866 | Transcriptional regulator (AraC/XylS family) for ara operon; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose. | Transcriptional regulator SprB (gi|5007028). | 0.499 |
barA | araC | STM2958 | STM0104 | Sensory histidine kinase; Similar to E. coli sensor-regulator, activates OmpR by phophorylation (AAC75828.1); Blastp hit to AAC75828.1 (918 aa), 90% identity in aa 1 - 918. | Transcriptional regulator (AraC/XylS family) for ara operon; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose. | 0.496 |
barA | fliZ | STM2958 | STM1955 | Sensory histidine kinase; Similar to E. coli sensor-regulator, activates OmpR by phophorylation (AAC75828.1); Blastp hit to AAC75828.1 (918 aa), 90% identity in aa 1 - 918. | Putative regulator of FliA; May regulate sigma factor activity. | 0.678 |
barA | hilD | STM2958 | STM2875 | Sensory histidine kinase; Similar to E. coli sensor-regulator, activates OmpR by phophorylation (AAC75828.1); Blastp hit to AAC75828.1 (918 aa), 90% identity in aa 1 - 918. | Regulatory helix-turn-helix proteins, araC family; HilD (gi|4455108). | 0.897 |
barA | invF | STM2958 | STM2899 | Sensory histidine kinase; Similar to E. coli sensor-regulator, activates OmpR by phophorylation (AAC75828.1); Blastp hit to AAC75828.1 (918 aa), 90% identity in aa 1 - 918. | Invasion protein; Transcriptional regulator required for the expression of several genes encoding type III secretion system SPI1 effector proteins. The interaction with SicA is necessary for the activation of sigDE (sopB pipC), sicAsipBCDA, and sopE. | 0.542 |
fliZ | araC | STM1955 | STM0104 | Putative regulator of FliA; May regulate sigma factor activity. | Transcriptional regulator (AraC/XylS family) for ara operon; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose. | 0.713 |
fliZ | barA | STM1955 | STM2958 | Putative regulator of FliA; May regulate sigma factor activity. | Sensory histidine kinase; Similar to E. coli sensor-regulator, activates OmpR by phophorylation (AAC75828.1); Blastp hit to AAC75828.1 (918 aa), 90% identity in aa 1 - 918. | 0.678 |
fliZ | hilD | STM1955 | STM2875 | Putative regulator of FliA; May regulate sigma factor activity. | Regulatory helix-turn-helix proteins, araC family; HilD (gi|4455108). | 0.937 |
fliZ | invF | STM1955 | STM2899 | Putative regulator of FliA; May regulate sigma factor activity. | Invasion protein; Transcriptional regulator required for the expression of several genes encoding type III secretion system SPI1 effector proteins. The interaction with SicA is necessary for the activation of sigDE (sopB pipC), sicAsipBCDA, and sopE. | 0.708 |
hilD | araC | STM2875 | STM0104 | Regulatory helix-turn-helix proteins, araC family; HilD (gi|4455108). | Transcriptional regulator (AraC/XylS family) for ara operon; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose. | 0.947 |
hilD | barA | STM2875 | STM2958 | Regulatory helix-turn-helix proteins, araC family; HilD (gi|4455108). | Sensory histidine kinase; Similar to E. coli sensor-regulator, activates OmpR by phophorylation (AAC75828.1); Blastp hit to AAC75828.1 (918 aa), 90% identity in aa 1 - 918. | 0.897 |
hilD | fliZ | STM2875 | STM1955 | Regulatory helix-turn-helix proteins, araC family; HilD (gi|4455108). | Putative regulator of FliA; May regulate sigma factor activity. | 0.937 |
hilD | invF | STM2875 | STM2899 | Regulatory helix-turn-helix proteins, araC family; HilD (gi|4455108). | Invasion protein; Transcriptional regulator required for the expression of several genes encoding type III secretion system SPI1 effector proteins. The interaction with SicA is necessary for the activation of sigDE (sopB pipC), sicAsipBCDA, and sopE. | 0.957 |
hilD | prgH | STM2875 | STM2874 | Regulatory helix-turn-helix proteins, araC family; HilD (gi|4455108). | Cell invasion protein; Required for invasion of epithelial cells. | 0.978 |
hilD | sicA | STM2875 | STM2886 | Regulatory helix-turn-helix proteins, araC family; HilD (gi|4455108). | Surface presentation of antigens; Type III secretion-associated chaperone required for SipB and SipC stabilization. Prevents premature association of SipB with SipC, which may lead to their targeting for degradation. Along with InvF, required for transcription activation of sigDE (sopB pipC), sicAsipBCDA, and sopE. | 0.933 |