Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ygbMPutative endonuclease; Similar to E. coli orf, hypothetical protein (AAC75781.1); Blastp hit to AAC75781.1 (258 aa), 79% identity in aa 1 - 258; Belongs to the hyi family. (258 aa)    
Predicted Functional Partners:
ygbK
Putative tRNA synthase; Catalyzes the ATP-dependent phosphorylation of 3-oxo- tetronate to 3-oxo-tetronate 4-phosphate. Belongs to the four-carbon acid sugar kinase family.
 
 
 0.997
ygbJ
Similar to E. coli putative dehydrogenase (AAC75778.1); Blastp hit to AAC75778.1 (302 aa), 82% identity in aa 1 - 299.
 
 
 0.995
STM1009
Gifsy-2 prophage exodeoxyribonuclease; Exodeoxyribonuclease VIII homolog (gi|7467238).
      
 0.950
ygbI
Putative regulatory protein, deoR family; Similar to E. coli putative DEOR-type transcriptional regulator (AAC75777.1); Blastp hit to AAC75777.1 (265 aa), 86% identity in aa 11 - 263.
 
  
 0.941
ygbL
Similar to E. coli putative epimerase/aldolase (AAC75780.1); Blastp hit to AAC75780.1 (212 aa), 85% identity in aa 1 - 211.
 
  
 0.937
STM2914
Putative nucleoside-diphosphate-sugar epimerase; Similar to E. coli UDP-galactose-4-epimerase (AAC73846.1); Blastp hit to AAC73846.1 (338 aa), 25% identity in aa 1 - 162.
 
 
  0.935
ygbF
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75796.1); Blastp hit to AAC75796.1 (116 aa), 84% identity in aa 23 - 116.
      
 0.897
STM2913
Similar to E. coli putative transport protein (AAC75782.1); Blastp hit to AAC75782.1 (454 aa), 33% identity in aa 11 - 446.
  
    0.755
bigA
Putative surface-exposed virulence protein BigA (gi|5081595).
      
 0.727
gcl
Similar to E. coli glyoxylate carboligase (AAC73609.1); Blastp hit to AAC73609.1 (593 aa), 96% identity in aa 1 - 593; Belongs to the TPP enzyme family.
 
  
 0.638
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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