STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STM2920Similar to E. coli transcriptional regulator for cryptic hemolysin (AAC74714.1); Blastp hit to AAC74714.1 (146 aa), 27% identity in aa 1 - 135. (134 aa)    
Predicted Functional Partners:
STM1547
Putative marR-family transcriptional regulator.
      
 0.894
hpaR
4-hydroxyphenylacetate catabolism protein.
   
  
 0.841
STM3595
Putative phosphatase.
      
 0.839
STM2922
Putative 3-polyprenyl-4-hydroxybenzoate decarboxylase; Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives.
 
  
 0.641
emrR
Transcriptional repressor of emrAB operon; MarR family; similar to E. coli regulator of plasmid mcrB operon (microcin B17 synthesis) (AAC75731.1); Blastp hit to AAC75731.1 (176 aa), 93% identity in aa 1 - 175.
      
 0.591
pagD
PhoP regulated; Putative function in virulence. Could be involved in promoting S.typhimurium survival within macrophages.
      
 0.577
ugtL
Putative membrane protein; Homology with chitinase from Schizosaccharomyces; putative membrane protein UgtL (gi|4585341).
      
 0.577
marR
Transcriptional repressor of marRAB operon; Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site.
  
   
 0.539
STM2923
Putative cytoplasmic protein.
  
    0.525
STM2921
Putative flavoprotein; Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives. Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for phenolic acid decarboxylase.
  
  
 0.521
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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