Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ygbFPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75796.1); Blastp hit to AAC75796.1 (116 aa), 84% identity in aa 23 - 116. (98 aa)    
Predicted Functional Partners:
cas1
Putative cytoplasmic protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
 
 0.999
STM2940
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75799.1); Blastp hit to AAC75799.1 (226 aa), 35% identity in aa 3 - 159.
 
  
 0.997
STM2942
Putative transposase.
 
  
 0.996
STM2943
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75802.1); Blastp hit to AAC75802.1 (502 aa), 28% identity in aa 2 - 289.
 
  
 0.996
ygcB
Putative helicase; Similar to E. coli orf, hypothetical protein (AAC75803.1); Blastp hit to AAC75803.1 (888 aa), 30% identity in aa 7 - 849.
 
  
 0.996
yghJ
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75800.1); Blastp hit to AAC75800.1 (363 aa), 29% identity in aa 1 - 334.
 
  
 0.995
ygcH
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75798.1); Blastp hit to AAC75798.1 (199 aa), 28% identity in aa 3 - 198.
 
  
 0.994
STM1009
Gifsy-2 prophage exodeoxyribonuclease; Exodeoxyribonuclease VIII homolog (gi|7467238).
      
 0.910
ygbM
Putative endonuclease; Similar to E. coli orf, hypothetical protein (AAC75781.1); Blastp hit to AAC75781.1 (258 aa), 79% identity in aa 1 - 258; Belongs to the hyi family.
      
 0.897
bigA
Putative surface-exposed virulence protein BigA (gi|5081595).
     
 0.727
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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