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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ygcHPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75798.1); Blastp hit to AAC75798.1 (199 aa), 28% identity in aa 3 - 198. (216 aa)    
Predicted Functional Partners:
STM2940
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75799.1); Blastp hit to AAC75799.1 (226 aa), 35% identity in aa 3 - 159.
 
  
 0.998
cas1
Putative cytoplasmic protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.997
ygbF
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75796.1); Blastp hit to AAC75796.1 (116 aa), 84% identity in aa 23 - 116.
 
  
 0.996
STM2943
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75802.1); Blastp hit to AAC75802.1 (502 aa), 28% identity in aa 2 - 289.
 
  
 0.996
STM2942
Putative transposase.
 
  
 0.995
ygcB
Putative helicase; Similar to E. coli orf, hypothetical protein (AAC75803.1); Blastp hit to AAC75803.1 (888 aa), 30% identity in aa 7 - 849.
 
  
 0.995
yghJ
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75800.1); Blastp hit to AAC75800.1 (363 aa), 29% identity in aa 1 - 334.
 
  
 0.993
yggR
Similar to E. coli putative protein transport (AAC75987.1); Blastp hit to AAC75987.1 (341 aa), 79% identity in aa 16 - 341.
      
 0.833
STM0699
Putative cytoplasmic protein.
   
  
 0.810
stfC
Outer membrane usher protein StfC (gi|3747030).
   
  
 0.701
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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