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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STM2943Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75802.1); Blastp hit to AAC75802.1 (502 aa), 28% identity in aa 2 - 289. (518 aa)    
Predicted Functional Partners:
STM2940
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75799.1); Blastp hit to AAC75799.1 (226 aa), 35% identity in aa 3 - 159.
 
 
 0.999
yghJ
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75800.1); Blastp hit to AAC75800.1 (363 aa), 29% identity in aa 1 - 334.
 
 
 0.999
STM2942
Putative transposase.
 
 
 0.999
ygcB
Putative helicase; Similar to E. coli orf, hypothetical protein (AAC75803.1); Blastp hit to AAC75803.1 (888 aa), 30% identity in aa 7 - 849.
 
 
 0.999
cas1
Putative cytoplasmic protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.998
ygbF
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75796.1); Blastp hit to AAC75796.1 (116 aa), 84% identity in aa 23 - 116.
 
  
 0.997
ygcH
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75798.1); Blastp hit to AAC75798.1 (199 aa), 28% identity in aa 3 - 198.
 
  
 0.996
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.