Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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ygdEPutative SAM-dependent methyltransferase; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. (366 aa)    
Predicted Functional Partners:
ygdD
Putative small membrane protein; Similar to E. coli orf, hypothetical protein (AAC75849.1); Blastp hit to AAC75849.1 (131 aa), 90% identity in aa 1 - 131.
 
  
 0.991
gcvA
Regulator of gcv operon; LysR family; similar to E. coli positive regulator of gcv operon (AAC75850.1); Blastp hit to AAC75850.1 (305 aa), 98% identity in aa 1 - 305; Belongs to the LysR transcriptional regulatory family.
 
    0.895
yecP
Putative enzyme; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
   
  
 0.727
yhhL
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76491.1); Blastp hit to AAC76491.1 (89 aa), 86% identity in aa 1 - 89.
      
 0.726
ygdK
Putative SufE protein probably involved in Fe-S center assembly; Similar to E. coli orf, hypothetical protein (AAC75853.1); Blastp hit to AAC75853.1 (147 aa), 88% identity in aa 1 - 144.
 
    0.700
yjfH
Putative tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
  
  
 0.690
yfiH
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75642.1); Blastp hit to AAC75642.1 (243 aa), 87% identity in aa 1 - 243; Belongs to the multicopper oxidase YfiH/RL5 family.
   
  
 0.683
ycbY
Putative N6-adenine-specific DNA methylase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.
      
 0.665
trmJ
Putative rRNA methylase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
   
  
 0.660
yejK
Nucleotide associated protein; Present in spermidine nucleoids; similar to E. coli orf, hypothetical protein (AAC75247.1); Blastp hit to AAC75247.1 (335 aa), 96% identity in aa 1 - 334.
  
    0.652
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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