Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ppdBPrepilin peptidase dependent protein B; Putative component in type IV pilin biogenesis; similar to E. coli prepilin peptidase dependent protein B (AAC75864.1); Blastp hit to AAC75864.1 (187 aa), 67% identity in aa 3 - 187. (187 aa)    
Predicted Functional Partners:
ppdA
Prepilin peptidase dependent protein A; Putative component in type IV pilin biogenesis; similar to E. coli prepilin peptidase dependent protein A (AAC75865.1); Blastp hit to AAC75865.1 (156 aa), 65% identity in aa 1 - 155.
  
 
 0.998
ygdB
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75863.1); Blastp hit to AAC75863.1 (121 aa), 52% identity in aa 1 - 121.
  
  
 0.974
ppdC
Prepilin peptidase dependent protein C; Putative component in type IV pilin biogenesis; similar to E. coli prepilin peptidase dependent protein C (AAC75862.1); Blastp hit to AAC75862.1 (107 aa), 69% identity in aa 1 - 106.
  
  
 0.973
hofB
Putative integral membrane protein; Involved in biogenesis of fimbriae (type IV pilin), protein transport, DNA uptake; similar to E. coli putative integral membrane protein involved in biogenesis of fimbriae, protein transport, DNA uptake (AAC73218.1); Blastp hit to AAC73218.1 (461 aa), 69% identity in aa 1 - 459.
  
  
 0.932
ppdD
Prelipin peptidase dependent protein; Putative major component of type IV pilin; similar to E. coli prelipin peptidase dependent protein (AAC73219.1); Blastp hit to AAC73219.1 (146 aa), 89% identity in aa 1 - 146.
  
  
 0.858
hofC
Similar to E. coli putative integral membrane protein involved in biogenesis of fimbriae, protein transport, DNA uptake (AAC73217.1); Blastp hit to AAC73217.1 (400 aa), 67% identity in aa 1 - 400.
  
  
 0.836
smg
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76309.1); Blastp hit to AAC76309.1 (157 aa), 94% identity in aa 1 - 157; Belongs to the Smg family.
      
 0.815
recC
Exonuclease V, subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzy [...]
  
  
 0.782
yafV
Similar to E. coli putative EC 3.5. amidase-type enzyme (AAC73323.1); Blastp hit to AAC73323.1 (256 aa), 82% identity in aa 3 - 255.
      
 0.722
yfeD
Putative negative regulator; Similar to E. coli orf, hypothetical protein (AAC75456.1); Blastp hit to AAC75456.1 (130 aa), 70% identity in aa 1 - 129.
      
 0.718
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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