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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lysRPositive LysR family transcriptional regulator; Similar to E. coli positive regulator for lys (AAC75878.1); Blastp hit to AAC75878.1 (311 aa), 86% identity in aa 1 - 311; Belongs to the LysR transcriptional regulatory family. (311 aa)    
Predicted Functional Partners:
lysS
Similar to E. coli lysine tRNA synthetase, constitutive; suppressor of ColE1 mutation in primer RNA (AAC75928.1); Blastp hit to AAC75928.1 (505 aa), 95% identity in aa 1 - 505; Belongs to the class-II aminoacyl-tRNA synthetase family.
      
 0.897
lrhA
Similar to E. coli NADH dehydrogenase transcriptional regulator, LysR family (AAC75349.1); Blastp hit to AAC75349.1 (312 aa), 86% identity in aa 1 - 312; Belongs to the LysR transcriptional regulatory family.
  
     0.769
STM3834
Similar to E. coli putative transcriptional regulator LYSR-type (AAC73855.1); Blastp hit to AAC73855.1 (338 aa), 27% identity in aa 22 - 318; Belongs to the LysR transcriptional regulatory family.
  
     0.768
STM0859
Similar to E. coli putative transcriptional regulator LYSR-type (AAC74667.1); Blastp hit to AAC74667.1 (297 aa), 28% identity in aa 1 - 264; Belongs to the LysR transcriptional regulatory family.
  
     0.753
yifA
Putative LysR family transcriptional regulator; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
  
     0.748
yfiE
Similar to E. coli putative transcriptional regulator LYSR-type (AAC75630.1); Blastp hit to AAC75630.1 (308 aa), 78% identity in aa 16 - 305; Belongs to the LysR transcriptional regulatory family.
  
     0.730
yhcS
Similar to E. coli putative transcriptional regulator LYSR-type (AAC76275.1); Blastp hit to AAC76275.1 (309 aa), 95% identity in aa 1 - 309; Belongs to the LysR transcriptional regulatory family.
  
     0.726
tdcA
LysR family; similar to E. coli transcriptional activator of tdc operon (AAC76153.1); Blastp hit to AAC76153.1 (312 aa), 89% identity in aa 1 - 311; Belongs to the LysR transcriptional regulatory family.
  
     0.711
thrL
Thr operon leader peptide; This protein is involved in control of the biosynthesis of threonine.
 
 
    0.697
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
 
     0.682
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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