STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kduIPutative pectin degrading enzyme; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family. (278 aa)    
Predicted Functional Partners:
kduD
Similar to E. coli 2-deoxy-D-gluconate 3-dehydrogenase (AAC75881.1); Blastp hit to AAC75881.1 (253 aa), 93% identity in aa 1 - 253; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 0.999
uxuA
Putative mannonate hydrolase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family.
 
  
 0.924
kdgK
Similar to E. coli ketodeoxygluconokinase (AAC76551.1); Blastp hit to AAC76551.1 (382 aa), 92% identity in aa 74 - 381.
 
  
 0.910
uxaC
Similar to E. coli uronate isomerase (AAC76127.1); Blastp hit to AAC76127.1 (470 aa), 67% identity in aa 1 - 468.
 
  
 0.902
yaeQ
Putative cytoplasmic protein; Hypothetical 20.8 Kda protein in mesJ-cutF intergenic region. (SW:YAEQ_SALTY).
   
    0.900
lepB
Leader peptidase (signal peptidase I), serine protease; Signal peptidase I. (SW:LEP_SALTY); Belongs to the peptidase S26 family.
   
  
 0.896
parC
DNA topoisomerase IV, subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
    0.848
STM0869
Similar to E. coli putative DEOR-type transcriptional regulator (AAC73933.1); Blastp hit to AAC73933.1 (178 aa), 78% identity in aa 1 - 178.
   
    0.845
minE
Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
   
    0.820
cspC
Cold shock protein; Multicopy suppresses mukB mutants, putative regulator; cold shock-like protein CSPC. (SW:CSPC_SALTY).
   
    0.820
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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